Hesiod's Works and Days is undeniably a didactic poem. It is concerned with real problems of mankind. At a first glance it may seem as a practical guide to living and prospering in the Ancient Greek world. The title itself, along with the many parts of the poem that deal with practical issues can lead one to this conclusion. A more careful analysis, however, can show that Works and Days is more...

Peroral endoscopic myotomy (POEM) is the application of esophageal myotomy to the concept of natural orifice transluminal surgery (NOTES) by utilizing a submucosal tunneling method. Since the first case of POEM was performed for treating achalasia in Japan in 2008, this procedure is being more widely used by many skillful endosopists all over the world. Currently, POEM is a spotlighted, emergin...

A 54-year-old woman sought clinical consultation because of a > 27-year history of dysphagia. She had an Eckardt score of 13 and was diagnosed with sigmoid-type achalasia (S2 type, type II) based on esophageal motility testing, upper endoscopy, barium esophagography, and clinical presentations. We investigated a technique of peroral endoscopic myotomy (POEM) performed directly without a submuco...

BACKGROUND AND STUDY AIMS Peroral endoscopic myotomy (POEM) is a time-consuming and challenging procedure. Traditionally, the myotomy is done after the submucosal tunnel has been completed. Starting the myotomy earlier, after submucosal tunneling is half completed (concurrent myotomy and tunneling), may be more efficient. This study aims to assess if the method of concurrent myotomy and tunneli...

Associated with the renewal of funding in 2002, and the successful attainment of several of the studies early goals, the current goals of the study have been modified and now include the interaction of marine aerosols with marine boundary layer (MBL) clouds. New goals include: 1) assessment of the relative impacts of purely meteorological and aerosol factors on cloud albedo, 2) determination of...

BACKGROUND The Patient-Oriented Eczema Measure (POEM) is a validated, patient-derived assessment measure for monitoring atopic eczema severity, although further information on how different POEM scores translate into disease severity categories is needed for clinical trials, epidemiological research and audit. OBJECTIVES We sought to determine the relationship between Patient-Oriented Eczema ...

Peroral endoscopic myotomy (POEM) is a revolutionary therapy for achalasia and related disorders. POEM utilizes almost the same myotomy procedure as the Heller myotomy; thus, it would be expected to have the same or greater duration of therapeutic effect. However, to date, there have been no reports to prove the basis for this procedure in achalasia. In this case, we were able to histologically...

Worldwide, peroral endoscopic myotomy (POEM) has achieved remarkable initial outcomes in the treatment of achalasia. In China, POEM has developed very quickly since the first case was performed in our center in August 2010. With ex-perience, we have successfully performed POEM for special cases (such as pediatric patients, patients with sigmoid-type esophagus, and patients with recurrent sympto...