نتایج جستجو برای: srp
تعداد نتایج: 1831 فیلتر نتایج به سال:
مکان یابی منبع گفتار یکی از زیر شاخه های سیستم های پردازش گفتاری می باشد. در این پژوهش مکان یابی منبع گفتار با استفاده از روش های مبتنی بر srp مدنظر بوده است. روش استفاده شده در این پژوهش روش srp-phat است. روش srp-phat در مکان یابی منبع گفتار تحت شرایط انعکاسی، مقاوم می باشد. در حقیقت این روش که بر مبنای شکل دهی پرتو آرایه میکروفونی بنا نهاده شده است، سعی می کند با جستجوی فضا، ماکزیمم انرژی در ...
STRUCTURE OF THE SRP AND SRP RECEPTOR ........................... . NOlllelleiatllre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SRP RNA SRP Structllre alld Assembly ............................................ . SRP Proteill SlIbllllits . . . . . . .. . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . ....
Translocation of proteins across the endoplasmic reticulum membrane is a GTP-dependent process. The signal recognition particle (SRP) and the SRP receptor both contain subunits with GTP binding domains. One GTP-dependent reaction during protein translocation is the SRP receptor-mediated dissociation of SRP from the signal sequence of a nascent polypeptide. Here, we have assayed the SRP and the ...
Two experiments using novel complex working memory span tasks were performed, both requiring the participants to remember a span of letters whilst being distracted by the processing of words. Word processing could either be selfreferential (SRP) or not. In the first experiment recall performance was compared between SRP and non-SRP conditions using the same words. In the second experiment, we c...
Cotranslational protein targeting to membranes is regulated by two GTPases in the signal recognition particle (SRP) and the SRP receptor; association between the two GTPases is slow and is accelerated 400-fold by the SRP RNA. Intriguingly, the otherwise universally conserved SRP RNA is missing in a novel chloroplast SRP pathway. We found that even in the absence of an SRP RNA, the chloroplast S...
The signal recognition particle (SRP) is an evolutionarily conserved ribonucleoprotein (RNP) complex that functions in protein targeting to the endoplasmic reticulum (ER) membrane. Only two protein subunits of the SRP, Srp54p and Sec65p, and the RNA subunit, scR1, were previously known in the yeast Saccharomyces cerevisiae. Purification of yeast SRP by immunoaffinity chromatography revealed fiv...
The bacterial signal recognition particle (SRP) binds to ribosomes synthesizing inner membrane proteins and, by interaction with the SRP receptor, FtsY, targets them to the translocon at the membrane. Here we probe the conformation of SRP and SRP protein, Ffh, at different stages of targeting by measuring fluorescence resonance energy transfer (FRET) between fluorophores placed at various posit...
The signal-recognition particle (SRP) is a ubiquitous protein-RNA complex that targets proteins to cellular membranes for insertion or secretion. A key player in SRP-mediated protein targeting is the evolutionarily conserved core consisting of the SRP RNA and the multidomain protein SRP54. Communication between the SRP54 domains is critical for SRP function, where signal sequence binding at the...
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