objective(s):cyclophosphamide (cp) toxicity on testis was hampered by squid ink polysaccharide (sip) via restoration of antioxidant ability in our previous investigations. this study investigated roles of nrf2/are signal pathway in testis of treated mice. materials and methods: male kunming mice were employed to undergo treatment with sip and/or cp. protein levels of nrf2, keap-1, histone deace...

Background The squid ink extract is well known for its biomedical properties. Objective In this study, squid Loligo vulgaris was collected from Tuticorin costal water, Bay of Bengal, India. Materials and Methods Proximate composition of the crude squid ink was studied and found to have protein as the major component over lipid and carbohydrates. Further, bioactive fractions of squid ink wer...

Chromatographic characterization and the GC-MS evaluation of the black pigmented ink of Loligo duvauceli in the present study have yielded an array of bioactive compounds with potent antimicrobial property. Facing an alarm of antimicrobial resistance globally, a need for elucidating antimicrobial agents from natural sources will be the need for the hour. In this view, this study is aimed at cha...

Chemical and visual defenses are used by many organisms to avoid being approached or eaten by predators. An example is inking molluscs-including gastropods such as sea hares and cephalopods such as squid, cuttlefish, and octopus-which release a colored ink upon approach or attack. Previous work showed that ink can protect molluscs through a combination of chemical, visual, and other effects. In...

The present study was conducted to investigate the preventive effects of squid ink polysaccharides (SIP) on the damage of sperm and reproduction induced by cyclophosphamide that is most commonly used for treating clinically cancers. Male Kunming mice exposed to cyclophosphamide were administered with SIP and were sacrificed to determine sperm parameters, testicular antioxidant ability and repro...

Objective(s):Cyclophosphamide (CP) toxicity on testis was hampered by squid ink polysaccharide (SIP) via restoration of antioxidant ability in our previous investigations. This study investigated roles of Nrf2/ARE signal pathway in testis of treated mice. Materials and Methods: Male Kunming mice were employed to undergo treatment with SIP and/or CP. Protein levels of Nrf2, keap-1, histone deac...