sprue (Chaudhuri and Rai Chaudhuri, 1944), nutritional diarrhoea (Karamchandani, 1944), incomplete sprue (Manson-Bahr, 1940), chronic jejuno-ileal insufficiency (Bennett and Hardwick, 1940), and vitamin B deficiency syndrome allied to sprue (Cook, 1944). Rogers (Rogers and Megaw, 1942) is of the view that unexplained diarrhoea of more than 10 days' duration should be treated as sprue, provided ...

Celiac and Tropical Sprue are malabsorptive diseases with similar clinical manifestations and histological findings. While, Celiac sprue is a known cause of malabsorption in the Western world, Tropical sprue is relatively uncommon and often overlooked by the medical community. Misdiagnosis can result in delay of adequate treatment in a patient with Tropical Sprue. We present a patient with a Tr...

3D CAD models of different variants of the sprue system design of an experimental optical disc mould are developed. The main purpose of the present work is to be predicted the correct geometry shape and parameters of the sprue system before these elements to be produced. The 3D CAD models are built as a combination of the polymer substrate and the sprue system, considered as one object. This ap...

Celiac sprue is a disorder characterized by the symptoms of malabsorption and an abnormal small bowel histology, which is due to the patient's intolerance to gluten. Gluten is a protein found in wheat and wheat products. The typical symptoms of malabsorption include weight loss, abdominal distention, bloating, diarrhea and steatorrhea. However, the severity of the disease varies greatly among t...

Epithelial barrier function and ion transport was studied in coeliac sprue using a miniaturised Ussing device for measurements on diagnostic aspiration biopsy specimens from the jejunum of untreated or gluten free nourished sprue patients, or from healthy controls. Pure epithelial resistance (Re) indicating epithelial barrier function was determined by transmural alternating current impedance a...

Tropical sprue has been described as occurring in both endemic and epidemic forms (Walters, 1947; Ayrey, 1948; Stefanini, 1948; Baker, 1957; Baker, Mathan, and Joseph, 1962). Bahr (1915) mentions 'sprue houses' where successive tenants were attacked with sprue, and records several cases occurring among members of one family. This paper presents epidemiological, clinical and laboratory data on a...

BACKGROUND Clonal T cell receptor (TCR) gene rearrangements and loss of T cell antigens such as CD8 and TCR-beta in intraepithelial lymphocytes (IELs) may indicate the development of an enteropathy-type intestinal T cell lymphoma (EITCL) in patients with refractory sprue. AIMS To define the diagnostic value of these markers in duodenal biopsies from patients with villous atrophy as a result o...

epithelium. A preexisting permeability defect may trigger the expression of celiac sprue by allowing ingested gluten to cross the epithelial barrier and incite a pathologic immune reaction in genetically susceptible individuals. Thus, one possible explanation for an association between IJFT and celiac sprue is an underlying systemic permeability defect that is responsible for both increased glu...

The effect of fat malabsorption on the absorption and renal excretion of dietary oxalate was studied in four patients with sprue and in two patients with dermatitis herpetiformis and sprue-like jejunal histology. Hyperoxaluria was present in all patients with sprue when fat malabsorption was severe. Urinary oxalate excretion decreased in two of the three patients with coeliac sprue when their f...

epithelium. A preexisting permeability defect may trigger the expression of celiac sprue by allowing ingested gluten to cross the epithelial barrier and incite a pathologic immune reaction in genetically susceptible individuals. Thus, one possible explanation for an association between IJFT and celiac sprue is an underlying systemic permeability defect that is responsible for both increased glu...