A study was conducted to evaluate the effectiveness of three selected botanicals namely leaf extract of Neem (Azadirachta indica), Debdaru (Polyalthia longifolia) and datura (black) (Datura metel) along with Bavistin (Carbendazim) and BAU-biofungicide (Trichoderma harzianum) against leaf spot disease (tikka) of groundnut caused by Cercospora arachidicola and Cercosporidium personatum at the Fie...

Aim: Chronic rhinosinusitis is an inflammatory disease of the nasal mucosa often occurring concurrently with dry eye. The aim was to assess the effects of Manuka (Leptospermum spp.) antibacterial honey nasal spray (Melcare® Manuka+TM Nasal Spray, Melcare, Australia) and eye drops (Optimel Manuka+ Dry Eye Drops, Melcare, Australia) on both conditions. The safety of and adherence to these treatme...

Pulmonary inhalation chemotherapeutic drug delivery offers many advantages for lung cancer patients in comparison to conventional systemic chemotherapy. Inhalable particles are advantageous in their ability to deliver drug deep in the lung by utilizing optimally sized particles and higher local drug dose delivery. In this work, spray-dried and co-spray dried inhalable lung surfactant-mimic PEGy...

Heated styling appliances, such as straightening irons, have grown in popularity in recent years, as have hair products such as heat-protection sprays. In this study we investigate whether the water in a heat-protection spray can affect the level of damage caused by heat styling. Tryptophan damage from heat styling was measured using fluorescence spectroscopy, and structural damage was investig...

OBJECTIVES To determine the efficacy of a new saliva substitute in spray form, for patients with dry mouth. STUDY DESIGN Thirty-seven patients with dry mouth were selected (16 males and 21 females), with an age of over 60 years and meeting the following inclusion criteria: xerostomia and hyposialia confirmed by sialometry (resting whole saliva / stimulated whole saliva). A new artificial sali...

A powder vaccine intended for aerosol delivery was formulated by spray drying the Ad35-vectored tuberculosis (TB) AERAS-402 vaccine with mannitol-based stabilizers. Thermodynamic properties, water absorption, particle size distribution and morphology of the powders were evaluated. Virus survival during spray drying and storage was determined by medium Tissue Culture Infectious Dose (TCID(50)). ...

Novel advanced spray-dried and co-spray-dried inhalable lung surfactant-mimic phospholipid and poly(ethylene glycol) (PEG)ylated lipopolymers as microparticulate/nanoparticulate dry powders of biodegradable biocompatible lipopolymers were rationally formulated via an organic solution advanced spray-drying process in closed mode using various phospholipid formulations and rationally chosen spray...

OBJECTIVE The aim of the present study is to evaluate the effect of ginger herbal spray on reducing dry mouth in patients with Type II diabetes. MATERIALS AND METHODS This clinical trial was conducted on 20 patients with Type II diabetes suffering from dry mouth. The control individual for each patient was the same patient himself/herself. Each patient filled out his/her questionnaire at thre...

A moisturising micro-gel spray for prevention of dryness was compared with commercial products and artificial saliva in vitro and in a clinical setting in patients with cancer. Survival of cultured human gingival epithelial cells was evaluated after treatment with each product for 15 min. A dry test was performed for products giving a 50% survival rate, in which cell survival was measured after...