background: today, cancer is one of the major health problems worldwide, and the importance of this disease in our country is growing. this cancer is the third cause of death and accounts for the second largest group of non-transmissible chronic diseases. colorectal cancer is the most common gastrointestinal cancer and includes 10%  of deaths from cancer around the world. different genetic and ...

background: the sporadic type of hemiplegic migraine (hm) is sometimes observed among migrainous patients (mp) and mimics ischemic strokes. methods: in an evaluation of two-hundred consecutive adult mp in the mackenzie headache clinic, canada during 2004 , 9% of the patients met the criteria established by the international headache society for sporadic hm. female to male sex ratio, family hist...

meningioangiomatosis is regarded as a rare benign hamartomatous condition mostly involving the cerebral cortex and overlying leptomeninges. a strong association of ma with neurofibromatosis type 2 has been documented in published articles. herein we report a case of an otherwise healthy 13-year-old boy with no family history or stigmata of neurofibromatosis who presented with intractable seizur...

aim : to investigate association between mthfr gene polymorphism with colorectal cancer. background : the enzyme 5,10-methylene-tetrahydrofolate reductase (mthfr) is linked to dna methylation, synthesis and repair. one of the most important polymorphisms that has been identified in the mthfr gene is c677t. the single nucleotide polymorphism c677t has been found to be associated with decreased e...

let $g$ be a finite group‎. ‎we say that $g$ has emph{spread} r if for any set of distinct non-trivial elements of $g$ $x:={x_1,ldots‎, ‎x_r}subset g^{#}$ there exists an element $yin g$ with the property that $langle x_i,yrangle=g$ for every $1leq ileq r$‎. ‎we say $g$ has emph{exact spread} $r$ if $g$ has spread $r$ but not $r+1$‎. ‎the spreads of finite simple groups and their decorations ha...

approximately 5-10% of all thyroid cancers are medullary thyroid carcinomas (mtc). mtc is mainly sporadic in nature, but 20-30% of cases are hereditary. genetic testing for hereditary mtc is very important for the patient and his family, but the patients must be receiving appropriate genetic counseling. about 98% of patients with hereditary mtc have germline mutations in exons 10, 11, 13, 14, 1...

MeduIIary thyroid carcinoma (MTC) occurs both sporadically and in the autosomal dominantly inherited multiple endocrine neoplasia (MEN) type 2 syndromes. The distinction between true sporadic MTC and a new mutation familial case is important for future clinical management of both the patient and family. The susceptibility gene for hereditary MTC is the RET proto-oncogene. DNA analysis for g...

the tp53 gene is one of the most frequently mutated genes amongst human malignancies, particularly tp53 codon 72 polymorphism. furthermore, an association between the tp53 codon 72 variants and prostate cancer has been reported in several studies. although some studies have indicated an association between the tp53 arg/arg variant and an increased risk for prostate cancer, other studies have sh...