Spinal tuberculosis is a very severe disease and causes increased rate of mortality and morbidity. Worldwide, this is a challenge for physicians to diagnose spinal tuberculosis. In this study we examine patients of different age groups, which are having various socio-economic status suffer from spinal tuberculosis which need to be evaluated successfully to help the physician with further manage...

in pott’s disease (tuberculous spondylitis), involvement of two separate levels of spine is rare. attention to stability of spine prevents delayed progressive kyphosis. a 12-year-old girl presented with neck pain, tenderness and swelling imaging showed cl—c2 and t9-t10 and destruction. mild spastic paraparesis was noticed. preoperative diagnosis was metastasis. t9, t10 and t11 laminectomy and c...

Background: The incidence of tuberculosis (TB) has increased in recent years in both developed and developing countries. Skeletal tuberculosis occurs in approximately 1% of patients with tuberculosis. The present study aimed to evaluate the epidemiology of skeletal tuberculosis in Golestan province in northeastern Iran during 2005-2014.Methods: In the present retrospective study, the epidemiolo...

Vitamin D deficiency and vitamin D receptor (VDR) gene abnormalities confer susceptibility to tuberculosis. Toll-like receptors (TLRs), such asTLR-2, are also important mediators of inflammatory response against Mycobacterium tuberculosis. We evaluated serum vitamin D, and VDR and TLR-2 gene polymorphisms in patients with spinal tuberculosis.This study comprised of 3 groups: spinal tuberculosis...

Spinal TB is a very dangerous type of skeletal TB as it can be.Focus on the diagnosis of spinal TB using radiographs, as this is the primary modality. Prod1.hul.harvard.educontenth482j21x5548q078fulltext.pdf. Gibbous.The dismal outcome of tuberculosis of the spine in the preantibiotic era has improved. Deficit and deformity are the worst complications of spinal tuberculosis.Any information cont...

This study investigated the diagnostic significance of urinary deoxypyridinoline measurement as a screening tool for spinal tuberculosis in patients with pulmonary tuberculosis.Urinary deoxypyridinoline levels were measured by automated chemiluminescence immunoassay and automated chemistry methods in patients with spinal (n=33) and pulmonary tuberculosis (n=33) and in healthy controls (n=30). U...

OBJECTIVE To correlate serum level of monocyte chemoattractant protein-1 (MCP-1) with postoperative recurrence of spinal tuberculosis in the Chinese Han population. METHODS Patients of Han nationality with newly diagnosed spinal tuberculosis were consecutively included in this study. At different time points postoperatively, serum level of MCP-1 was determined using an enzyme linked immunosor...

Natural history of posterior spinal tuberculosis has been described. Classifications of the posterior spinal tuberculosis disease process and principles of management based upon the clinical behavior of the disease has been highlighted and emphasized. A thorough review of literature was conducted with the aim to provide the clinicoradiological correlation of the natural history of posterior spi...

BACKGROUND DNA microarrays can detect tuberculosis and its multi-drug resistant form in M. tuberculosis isolates and sputum specimens with high sensitivity and specificity. However, no performance data currently exists for its use in spinal tuberculosis specimens. This study was aimed to assess the performance of the CapitalBio™ DNA microarray in the detection of isoniazid (INH) and rifampicin ...

conclusions after paravertebral implantation of rifapentine polylactic acid sustained-release microspheres, the concentration of rifapentine in local vertebral bone tissues was maintained above the tb minimum inhibitory concentration for up to 60 days with no apparent accumulation of the drug in other tissues. methods this study is a basic animal experimental study that began on july 17, 2014 i...