نتایج جستجو برای: sperm telomere length

تعداد نتایج: 350309  

Background: Telomeres are particular sequences of DNA located at the end of the eukaryotic chromosomes that are essential for genome integrity. Telomere length in spermatozoa differs among males, as well as spermatozoa. Also, decreased telomere length in spermatozoa of infertile men is associated with the reduction of fertility potential and embryo quality. Density gradient centrifugation (DGC)...

Journal: :Human reproduction 2013
A Ferlin E Rampazzo M S Rocca S Keppel A C Frigo A De Rossi C Foresta

STUDY QUESTION What are the relationships between telomere lengths in leukocytes and sperm, sperm count and parents' age at conception in a group of apparently healthy subjects of the same age? SUMMARY ANSWER Sperm telomere length (STL) is related to sperm count, it is lower in oligozoospermic than in normozoospermic men and it is directly related to parents' age at conception. WHAT IS KNOW...

Journal: :Reproductive biomedicine online 2015
Qingling Yang Nan Zhang Feifei Zhao Wanli Zhao Shanjun Dai Jinhao Liu Ihtisham Bukhari Hang Xin Wenbing Niu Yingpu Sun

The ends of eukaryotic chromosomes contain specialized chromatin structures called telomeres, the length of which plays a key role in early human embryonic development. Although the effect of sperm preparation techniques on major sperm characteristics, such as concentration, motility and morphology have been previously documented, the possible status of telomere length and its relation with spe...

Journal: :iranian journal of radiation research 0
j. zhang department of radiation oncology (chest section), shandong's key laboratory of radiation oncology, shandong cancer hospital, shandong university, jinan, 250117, p. r. china j. wang department of radiation oncology (chest section), shandong's key laboratory of radiation oncology, shandong cancer hospital, shandong university, jinan, 250117, p. r. china x. heng linyi people hospital, affiliated to shandong university, school of medicine, no. 27 jiefang road, linyi, 276000, shandong province, 250012 p. r. china x. heng linyi people hospital, affiliated to shandong university, school of medicine, no. 27 jiefang road, linyi, 276000, shandong province, 250012 p. r. china x. heng linyi people hospital, affiliated to shandong university, school of medicine, no. 27 jiefang road, linyi, 276000, shandong province, 250012 p. r. china

background: this study evaluated the relation between telomere length in lymph node (ln) and prognosis of esophageal squamous cell carcinoma (escc).  materials and methods: lns collected from 50 patients were assessed by pathological examination and quantitative reverse transcription polymerase chain reaction (qrt-pcr), which was used for detecting telomere length. the relation between clinical...

2015
Abraham Aviv Jeremy D. Kark Ezra Susser

Human telomere length, as expressed in leukocytes, is strongly fashioned by heritability. A number of genes that explain some of the inter-individual variation in leukocyte telomere length have already been identified. Leukocyte telomere length is longer in women than in men and in African Americans than in whites of european descent. in addition, offspring of older fathers display a longer leu...

2008
Masayuki Kimura Lynn F Cherkas Bernet S Kato Serkalem Demissie Jacob B Hjelmborg Michael Brimacombe Adrienne Cupples Janice L Hunkin Jefferey P Gardner Xiaobin Lu Xiaojian Cao Malinee Sastrasinh Michael A Province Steven C Hunt Kaare Christensen Daniel Levy Tim D Spector Abraham Aviv

Leukocyte telomere length (LTL) is a complex genetic trait. It shortens with age and is associated with a host of aging-related disorders. Recent studies have observed that offspring of older fathers have longer LTLs. We explored the relation between paternal age and offspring's LTLs in 4 different cohorts. Moreover, we examined the potential cause of the paternal age on offspring's LTL by deli...

Journal: :Human molecular genetics 2006
Duncan M Baird Bethan Britt-Compton Jan Rowson Nazar N Amso Linda Gregory David Kipling

Telomeres play a key role in upholding the integrity of the genome, and telomerase expression in spermatogonial stem cells is responsible for the maintenance of telomere length in the human male germline. We have previously described extensive allelic variation in somatic cell telomere length that is set in the zygote, the ultimate source of which may be the germline. This implies that despite ...

J. Wang, J. Zhang, L. Li, X. Heng, Z. Li,

Background: This study evaluated the relation between telomere length in lymph node (LN) and prognosis of esophageal squamous cell carcinoma (ESCC).  Materials and Methods: LNs collected from 50 patients were assessed by pathological examination and quantitative reverse transcription polymerase chain reaction (qRT-PCR), which was used for detecting telomere length. The relation between cli...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید