Actins play essential roles in cellular morphogenesis. In mice, the t-actin 1 and 2 genes, which encode actin-like proteins, are specifically expressed in haploid germ cells. Both T-ACTIN 1/ACTLB and T-ACTIN 2/ACTL7A have also been cloned as orthologous genes in humans; they are present on chromosome 9q31.3 as intronless genes. Defects of germ cell-specific genes can introduce infertility witho...

Abstract The monomeric (G-actin) and polymer (F-actin) forms of actin play important role in muscle development contraction, cellular motility, division, transport processes. Leiomodins 1–3 (Lmod1–3) are crucial for the sarcomeres. Unlike tropomodulins that localize only at pointed ends, striated specific Lmod2 shows diffuse distribution along entire length thin filaments. G-actin-binding profi...

The mechanism that mediates the interaction between contractile ring and plasma membrane during cytokinesis remains elusive. We previously found ERM (Ezrin/Radixin/Moesin) proteins, which usually mediate cellular pole contraction, become over-accumulated at cell equator support furrow ingression upon loss of other actin-membrane associated anillin supervillin. In this study, we addressed molecu...

introduction the application of immunohistochemical method has resulted in marked improvement of the microscopic diagnosis of neoplasms combined with h&e; staining. although unique cellular antigens have not been found in salivary gland neoplasms, multiple less specific immunomarkers have been used and may be helpful in elucidating the role of myoepithelial differentiation in those neoplasms. t...

Biological phenomena induced by terahertz (THz) irradiation are described in recent reports, but underlying mechanisms, structural and dynamical change of specific molecules still unclear. In this paper, we performed time-lapse morphological analysis human cells found that THz halts cell division at cytokinesis. At the end cytokinesis, contractile ring, which consists filamentous actin (F-actin...

Plasma membrane H+-ATPase is a major integral membrane protein with a role in various physiological processes including abiotic stress response. To study the effect of NaCl on the expression pattern of a gene encoding the plasma membrane H+-ATPase, an experiment was carried out in a completely random design with three replications. A pair of specific primers was designed based on the sequence o...