نتایج جستجو برای: somatic mutation

تعداد نتایج: 325275  

Journal: :iranian biomedical journal 0
ایثار نصیری issar nassiri مهری فقیهی mehri faghihi منوچهر توسلی manoochehr tavassoli

background: pharmacogenomics is the study of genetic variations among individuals to predict the probability that a patient will respond to single or multidrug chemotherapy. breast cancer is one of the most common cancers among women worldwide. treatment of breast cancer by application of biological rationales gives us the ability to match the correct pharmacology to individual tumour genetic p...

Journal: :caspian journal of environmental sciences 2009
k. vijayan s.n. chatterjee c.v. nair

genetic diversity among plants sprouted from seven year old clones of mulberry (morus indica var. s36) was studied using molecular markers such as issr and rapd. the clones showed significant variability in sex expression and the sprouting behavior. these changes were appeared after seven years of rigorous pruning and training (pruned once in every 3-4months). genetic diversity analysis reveale...

Journal: :American Journal of Clinical Pathology 2013

Journal: :Genome Biology 2002

Journal: :Gut 2003
M Miyaki T Iijima M Ohue Y Kita T Hishima T Kuroki T Iwama T Mori

During a search for causative genes in patients with concurrent multiple primary colon tumours, we found a novel case with a germline mutation of the p53 gene, from GCC (Ala) to GTC (Val) at codon 189. Of the six primary colon tumours that this patient had, one large advanced carcinoma exhibited a somatic p53 mutation and a somatic APC mutation, in addition to the germline p53 mutation. Two ear...

Journal: :Peer community in genomics 2022

A recommendation of: Sylvain Schmitt, Thibault Leroy, Myriam Heuertz, Niklas Tysklind Somatic mutation detection: a critical evaluation through simulations and reanalyses in oaks https://doi.org/10.1101/2021.10.11.462798

Journal: :middle east journal of rehabilitation and health studies 0
sanambar sadighi hematologist and medical oncologist, cancer research center, tehran university of medical sciences, tehran, ir iran issa jahanzad pathologist, pathology department, imam khomeini hospital, tehran university of medical sciences, tehran, ir iran mohammad ali mohagheghi surgeon, cancer research center, tehran university of medical sciences, tehran, ir iran mahdieh shokrollahi barough cancer research center, department of immunology, semnan university of medical sciences, semnan, ir iran; student’s research committee, semnan university of medical sciences, semnan, ir iran mohammad hojjat-farsangi department of oncology-pathology, immune and gene therapy lab, cancer center karolinska (cck), karolinska university hospital solna and karolinska institute, stockholm, sweden; department of immunology, school of medicine, bushehr university of medical sciences, bushehr, ir iran kazem zendehdel cancer research center of cancer institute of iran, tehran university of medical sciences, tehran, ir iran

conclusions according to this study, igvh3 mutation was found to be prevalent (although a correlation was found to exist between the patients’ survival and igvh mutation, it was not statistically significant). we can conclude that clinical methods are still valuable to predict the prognosis of patients with cll. given the high cost and need for specialized laboratory, determining the cost and v...

Indranil Choudhuri , Kalyani Khanra, Nandan Bhattacharyya,

Background: DNA polymerase β (pol β) is a key enzyme of base excision repair pathway. It is a 1-kb gene consisting of 14 exons. Its catalytic part lies between exon 8 and exon 14. Exon 12 has a role in deoxyribonucleotide triphosphate selection for nucleotide transferase activity. Methods: Genomic DNA was isolated from ovarian carcinoma samples. Single strand conformation polymorphism...

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