in this study, the ion association phenomenon in the saturated solution of kcl in the mixed solvent(methanol+water) was studied. the solubility of this compound in the mixed solvent (methanol+water by value percent of methanol = 60%), and in the presence of various molarities of nano3 wasdetermined by the solvent evaporation method at 25.0°c. the results enable us to estimate the valueof thermo...

Poor water solubility for many drugs and drug candidates remains a major obstacle to their development and clinical application. Conventional formulations to improve solubility suffer from low bioavailability and poor pharmacokinetics, with some carriers rendering systemic toxicities (e.g. Cremophor(®) EL). In this review, several major nanonization techniques that seek to overcome these limita...

A series of basic carboxamides of actagardine (1), a lantibiotic possessing good antistreptococcal activity, were synthetized. Some physico-chemical characteristics, in particular charge and lipophilicity, that influence water solubility were determined. The in vitro and in vivo activity was evaluated. The monocarboxamides were generally more active than actagardine against selected Gram-positi...

the extended hildebrand solubility parameter approach (ehsa) is used to estimate the solubility of satranidazole in binary solvent systems. the solubility of satranidazole in various water-peg 400 mixtures was analyzed in terms of solute-solvent interactions using a modified version of hildebrand-scatchard treatment for regular solutions. the solubility equation employs term interaction energy ...

barium sulfate (barite) is one of the widely used weighting materials in the preparation of drilling fluid for deep oil and gas wells. barite is not soluble in the regular solvents; such as, hydrochloric acid (hcl) and other acids. therefore, in this study, we focused on evaluating the dissolution of the industrial barite particles in different chelating agents. chelating agents; such as, dieth...

The properties of a variety of mouth protectors and sheet materials used to fabricate custom mouth protectors were determined in order to recommend limits for a specification. Hardness, water sorption, water solubility, impact absorption, and tear strength were measured, and limits for these properties were suggested.

The solubility of naproxen in binary mixtures of polyethylene glycol 200 (PEG 200) + water at the temperature range from 298.0 K to 318.0 K were reported. The combinations of Jouyban-Acree model + van’t Hoff and Jouyban-Acree model + partial solubility parameters were used to predict the solubility of naproxen in PEG 200 + water mixtures at different temperatures. Combination of Jouyban-Acree m...