BACKGROUND The quality-switched ruby laser (QSRL) has been widely used for the treatment of pigmented lesions, but clinical evaluations in most studies have been conducted on macroscopic skin color observation comparing the laser-treated skin with its nontreated surrounding area. A few investigations examined skin changes after laser therapy at a cellular level, but almost none did so noninvasi...

Introduction: Solar lentigo is local and benign proliferation of melanocytes which is common in old individuals and creates a major concern considering beauty. Despite several and somehow expensive treatments such as laser and cryotherapy, chemical peeling with Trichloroacetic Acid (TCA) has recently attracted attentions considering its low cost and availability. The present study was des...

Commentary | Dermatol Pract Concept 2013;4(1):5 43 Have we really concluded what a large cell acanthoma is? Is it a distinct entity, a solar lentigo, a subtype of seborrheic keratosis, or an HPV-induced acanthoma? In 1970, large cell acanthoma (LCA) was first described by Pinkus, as a sharply demarcated, hyperkeratotic patch, often on sun-exposed skin, characterized by extraordinarily large cel...

Background and aim: It is possible to use light sources suxh as lasers to destruct melanosomes and treat pigmented skin lesions. One of the most commonly used laser systems is Q switched ruby laser with a wave-length of 694 nm. This study was performed to evaluate the efficacy of the Q switched ruby laser in the treatment of pigmented skin lesions including lentigines (simplex or solar) and caf...

A solar lentigo is a flat, sharply circumscribed patch. It can be round, oval or irregular in shape. Color varies from skincolored, brown to dark brown or black, and size varies from a few millimeters to several centimeters in diameter [1, 2]. It results from long-term exposure to Ultraviolet (UV) radiation, which causes local proliferation of epidermal melanocytes and accumulation of melanin w...

Solar lentigines are benign, brownish lesions that occur on light exposed skin surfaces from age 30 onwards, as a sign of photoaging. As they are of cosmetic importance to many patients, different therapeutic modalities have been tried to remove these unwanted spots. The recent development of short-pulsed, pigment-specific lasers has enabled physicians to selectively destroy the pigment within ...

Facial lentigo maligna melanoma can be a diagnostic challenge in daily clinical practice as it has similar clinical and morphological features to other lesions such as solar lentigines and pigmented actinic keratoses. Confocal microscopy is a noninvasive technique that provides real-time images of the epidermis and superficial dermis with cellular-level resolution. We describe 3 cases of suspec...

LM: Lentigo maligna pAK: pigmented actinic keratosis RCM: reflectance confocal microscopy M elanoma on sun-damaged skin, commonly known as lentigo maligna (LM, akin to melanoma in situ) and lentigo maligna melanoma (akin to invasive melanoma), is mostly found on the head and neck of elderly patients. This type of melanoma, particularly when found early, may be difficult to diagnose on clinical ...