BACKGROUND The National Toxicology Program (NTP) performed short-term toxicity studies of tetra- and pentavalent vanadium compounds, vanadyl sulfate and sodium metavanadate, respectively. Due to widespread human exposure and a lack of chronic toxicity data, there is concern for human health following oral exposure to soluble vanadium compounds. OBJECTIVES To compare the potency and toxicologi...

Type 2 diabetes mellitus is a chronic, progressive illness that causes considerable morbidity and premature mortality. Vanadium is a trace mineral that has been claimed to be effective in controlling blood glucose levels in diabetic patients. A randomised placebo-controlled study was conducted to evaluate the effect of sodium metavanadate on selected biochemical markers in type 2 diabetic patie...

The behaviour of Mg related to vanadium(V)-induced lipid peroxidation (LPO) under in vitro conditions was examined. The studies performed on the liver supernatants (LS) obtained from control, sodium metavanadate-intoxicated, and sodium metavanadate-magnesium sulphate-administered male Wistar rats revealed and confirmed the pro-oxidative potential of V. Simultaneously, they indicated that the im...

The effects of different doses of ammonium metavanadate on the biochemical, haematological, hormonal and histopathological parameters of stilbesterol treated female Wistar rats were investigated. Ammonium metavanadate in the dose range 0-6 mg/kg caused a bi-phasic and time-dependent response on the acid [total and prostate] phosphatase. Furthermore ammonium metavanadate caused a dose-dependent ...

background and objective type 2 diabetes mellitus is a chronic, progressive illness that causes considerable morbidity and mortality. despite recent technical advances in therapy, more people are using alternative therapies. in this study evaluated the effect of sodium metavanadate on glucose levels and lipid profile in type 2 diabetes mellitus patients.   methods this is a randomized, controll...

type 2 diabetes mellitus is a chronic illness causing considerable morbidity and mortality. enormous advances have been made in medical care but more people are still having tendency to use herbal or alternative remedies. this study is a randomized, controlled trial on type 2 diabetic patients. the subject consisted of 60 patients divided randomly into three groups and supple-mented daily with ...