a simple and efficient one-pot method for the preparation of aromatic iodides has been developed by sequential diazotization–iodination of aromatic amines employing sodium nitrite and sodium iodide in the presence of acidic ionic liquid n-methyl-2-pyrrolidonum hydrosulfate ([h-nmp]hso4). the diazonium salts that are formed by this ionic liquid are stable at room temperature and react rapidly wi...

introduction: effective debridement of the root canal system with chemical irrigants prior to obturation is the key to long-term success of endodontic therapy. the purpose of this study is to compare the antibacterial activity of 2.5% sodium hypochlorite (naocl) and 2% iodine potassium iodide (iki) solutions as intracanal disinfectant in infected root canals during one-visit endodontic treatmen...

The absence of TSH-stimulated radioiodide uptake in differentiated thyroid cancer is associated with a high recurrence rate and reduced survival. We studied regulation of the sodium/iodide symporter gene in human papillary thyroid cancer cell lines (BHP) and primary human thyroid cells. BHP cells expressed very low levels of sodium/iodide symporter mRNA and did not concentrate iodide, but iodid...

sodium iodide-131 is administrated for treatment of hyperthyroidism and thyroid cancer. iodine-131 has multiple routs of excretion (urine, saliva, sweat, milk, feces, exhalation) from the body. patients receiving sodium iodide-131 therapy exposes other persons and the environment to unwanted radiation and contamination. the major source of radiation dose from administration of iodine-131 is ext...

Sodium Iodide-131 is administrated for treatment of hyperthyroidism and thyroid cancer. Iodine-131 has multiple routs of excretion (Urine, saliva, sweat, milk, feces, exhalation) from the body. Patients receiving Sodium Iodide-131 therapy exposes other persons and the environment to unwanted radiation and contamination. The major source of radiation dose from administration of Iodine-131 ...

A simple and efficient one-pot method for the preparation of aromatic iodides has been developed by sequential diazotization–iodination of aromatic amines employing sodium nitrite and sodium iodide in the presence of acidic ionic liquid N-methyl-2-pyrrolidonum hydrosulfate ([H-NMP]HSO4). The diazonium salts that are formed by this ionic liquid are stable at room temperature and r...

The junior writer first broached the subject of intravenous injections of sodium iodide for the treatment of goitre with a view to testing:? (1) Whether sodium iodide orally was beneficial in cases of goitre. (2) Whether iodine is essential for the good functioning of the thyroid gland. (3) Whether the oral administration of sodium iodide could prevent the disease. He suggested that it might be...

Thyroid hormones are essential for normal development and metabolism. Thyroid hormone biosynthesis requires iodide uptake into the thyrocytes and efflux into the follicular lumen, where it is organified on selected tyrosyls of thyroglobulin. Uptake of iodide into the thyrocytes is mediated by an intrinsic membrane glycoprotein, the sodium-iodide symporter (NIS), which actively cotransports two ...

BACKGROUND Methylation of sodium iodide symporter promoter has been reported to increase the incidence of papillary thyroid carcinoma (PTC). In this meta-analysis stratified via methylation of sodium iodide symporter promoter, we evaluate the relationship between methylation of sodium iodide symporter promoter and PTC. The association between methylation with aggressiveness and metastasis poten...