نتایج جستجو برای: sledai

تعداد نتایج: 798  

2017
Noémi Györi Ioanna Giannakou Katerina Chatzidionysiou Laurence Magder Ronald F van Vollenhoven Michelle Petri

OBJECTIVE To describe SLE disease activity patterns in the Hopkins Lupus Cohort. METHODS Disease activity was studied in 1886 patients followed-up for 1-28 years. Disease activity patterns were defined using (1) Physician Global Assessment (PGA) and (2) modified SLE Disease Activity Index (M-SLEDAI) as follows: long quiescent (LQ), M-SLEDAI=0/PGA=0 at all visits; relapsing-remitting (RR), per...

2011
Chee-Seng Yee Vernon T. Farewell David A. Isenberg Bridget Griffiths Lee-Suan Teh Ian N. Bruce Yasmeen Ahmad Anisur Rahman Athiveeraramapandian Prabu Mohammed Akil Neil McHugh Christopher Edwards David D’Cruz Munther A. Khamashta Caroline Gordon

OBJECTIVES To examine SLEDAI-2000 cut-off scores for definition of active SLE and to determine the sensitivity to change of SLEDAI-2000 for the assessment of SLE disease activity and minimal clinically meaningful changes in score. METHODS Data from two multi-centre studies were used in the analysis: in a cross-sectional and a longitudinal fashion. At every assessment, data were collected on S...

Journal: :iranian red crescent medical journal 0
zahra mirfeizi associate professor of rheumatology, rheumatic diseases research center, imam reza hospital, school of medicine, mashhad university of medical sciences, mashhad, ir iran hoorak poorzand assistant professor of cardiology, echocardiologist, atherosclerosis prevention research center, imam reza hospital, school of medicine, mashhad university of medical sciences, mashhad, ir iran; echocardiologist, atherosclerosis prevention research center, imam reza hospital, school of medicine, mashhad university of medical sciences, mashhad, ir iran. tel/fax: +98-5138544504 aida javanbakht school of medicine, mashhad university of medical sciences, mashhad, ir iran mohammad khajedaluee department of community medicine and public health, faculty of medicine, mashhad university of medical sciences, mashhad, ir iran

background systemic lupus erythematosus (sle) is an autoimmune connective-tissue disease involving multiple organs and systems. some evidence has demonstrated that disease activity could be associated with increased risk of organ damage. objectives the aim of this study was to determine the association between systemic lupus erythematosus disease activity index (sledai) scores and subclinical c...

Journal: :Annals of the rheumatic diseases 2008
C-S Yee D A Isenberg A Prabu K Sokoll L-S Teh A Rahman I N Bruce B Griffiths M Akil N McHugh D D'Cruz M A Khamashta P Maddison A Zoma C Gordon

OBJECTIVE To assess the reliability of Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)-2000 index in routine practice and its ability to capture disease activity as compared with the British Isles Lupus Assessment Group (BILAG)-2004 index. METHODS Patients with systemic lupus erythematosus from 11 centres were assessed separately by two raters in routine practice. Disease activit...

Journal: :Rheumatology 2000
M J Mirzayan R E Schmidt T Witte

OBJECTIVE To characterize prognostic parameters for systemic lupus erythematosus (SLE) flares. METHODS In a prospective study, 120 SLE patients attending our out-patient clinic were evaluated every 3 months for 2 yr. At every visit clinical manifestations and laboratory parameters were assessed and the SLE disease activity index (SLEDAI) was determined. A correlation analysis of the number of...

2014
Mircea Niculae Penescu Corina-Daniela Ene (Nicolae) Emanoil Ceauşu Ilinca Nicolae

Methods Serum level of GSTpi was quantified by immunoenzymatic method in 42 patients with active systemic lupus erythematous (based on SLEDAI score), without any treatment divided in two groups: Group A – 30 cases with active SLE (SLEDAI = 11.2 ± 3.2), with chronic C hepatitis; Group B – 12 cases with active SLE (SLEDAI = 12.1 ± 4.5) without hepatitis C. The results were compared to those obtai...

2012
Susan Manzi Jorge Sánchez-Guerrero Joan T Merrill Richard Furie Dafna Gladman Sandra V Navarra Ellen M Ginzler David P D'Cruz Andrea Doria Simon Cooper Z John Zhong Douglas Hough William Freimuth Michelle A Petri

OBJECTIVE To evaluate the effects of belimumab versus placebo, plus standard systemic lupus erythematosus (SLE) therapy, on organ domain-specific SLE disease activity. METHODS Data obtained after 52 weeks of treatment from two phase III trials (BLISS-52 and BLISS-76) comparing belimumab 1 and 10 mg/kg versus placebo, plus standard therapy, in 1684 autoantibody-positive patients were analysed ...

2017

Figure 3 is not correct in the published article. The correct Figure 3 is shown below. Figure 3: Hierarchical clustering of non-classical monocytes from patients and controls, with tracks indicating individuals, IFN score, SLEDAI score and prednisone usage. Each single cell forms a single row, and each column corresponds to an individual gene. All non-classical cells and genes are shown. Lower ...

2017
C Singgih Wahono Cameleia Diah Setyorini Handono Kalim Nurdiana Nurdiana Kusworini Handono

Background Curcumin contained in Curcuma xanthorrhiza is an immunomodulator that has similar biological effect as vitamin D. Combination of curcumin and vitamin D3 is expected to work synergistically. Objective To determine the effect of Curcuma xanthorrhiza supplementation on vitamin D3 administration to SLEDAI, IL-6, and TGF-β1 serum in SLE patients with hypovitamin D. Methods This was a ...

Journal: :Rheumatology 2015
Penny Watson Alan Brennan Helen Birch Hong Fang Michelle Petri

OBJECTIVE The aim of this study was to develop an SLE disease model that simulates long-term outcomes of SLE to estimate the long-term effectiveness and cost-effectiveness of SLE treatments. METHODS Longitudinal data from 1354 patients from the Hopkins Lupus Cohort were included in the analysis. Statistical models were created to estimate disease activity [Safety of Estrogen in Lupus Erythema...

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