allergy diagnosis needs to be improved in polysensitized patients due to the existence of possible confounding factors in this type of patients. component resolved diagnosis (crd) is a new concept in the investigation of polysensitized patients. the aim of this study was to evaluate if the utilization of immunocap isac improve the diagnosis of the polysensitized allergic rhinitis patients. skin...

ige- mediated food allergy affects 6-8% of children. our study aimed to define the correlations between the results obtained with skin prick tests (spts) using commercial extracts and fresh foods, and the correlations between these result and those obtained with specific ige (sige) and/ or challenge. children aged from 2 months to 6 years were recruited prospectively. overall 571 children were ...

component-resolved  diagnosis (crd) using microarray technology has recently been introduced  with the  aim to  improve diagnosis of allergy. the  aim of this study was to compare performance of this allergen microarray to those of an established extract-based skin prick testing (spt). 45  patients  with  allergic rhinitis  were studied  (16 children  and  29  adults). spt  to dermatophagoides ...

In today's clinical practice patients' skin is used as screening organ for diagnosing type 1 allergy. According to European guidelines skin prick testing with a panel of 18 allergen extracts is recommended, in the US between 10 to 50 allergens are used. The specificity and sensitivity of skin testing is individually highly variable depending on age, body mass, and skin barrier status. In atopic...

Skin prick testing is widely used to predict the presence of allergen-specific IgE. In eosinophilic esophagitis patients, who frequently exhibit polysensitization and broad reactivity upon skin prick testing, this is commonly used to aid avoidance recommendations in the clinical management of their disease. We present here the predictive value of skin prick testing for the presence of allergen-...

the pathogenetic mechanism of nasal polyps remains unknown, although allergy has been cited as an important factor in the etiology of nasal polyposis. currently there is no definite histological criterion for differentiation of allergic from inflammatory nasal polyp. however, in a few studies, tissue eosinophil count has been used for this. this study aimed to find out the agreement rate of ski...

Skin testing is a reliable and safe way to diagnose IgE-mediated allergies, with rare side-effects. Two cases of systemic allergic reactions during skin testing to food allergens are hereby reported. A 28-year-old male reported allergic reactions, mild to moderate in severity, each time he tasted fish in the frame of his professional duties. During SPT and prick-to-prick to raw and cooked fishe...