نتایج جستجو برای: single cycle replicable virion scr

تعداد نتایج: 1135219  

Journal: :international journal of molecular and clinical microbiology 0
yassaman eftekhari department of biochemistry, college of basic sciences, tehran, science and research branch, islamic azad university, tehran, iranسازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch) a rustaiyan department of chemistry, college of basic sciences, tehran, science and research branch, islamic azad university, tehran, iran.سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch) m monajjemi department of chemistry, college of basic sciences, tehran, science and research branch, islamic azad university, tehran, iran.سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch) r. a khavari-nejad department of biology, college of basic sciences, tehran, science and research branch, islamic azad university, tehran, iranسازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch)

human immunodeficiency virus (hiv) infection is the major problem in the world. nowadays, new anti-retroviral drugs are extracted from medicinal plants, make an important role to supersede synthetic drugs with different side effects. in this study, we studied the salix aegyptiaca l extract, iranian herb, as an anti-hiv drug with anti-retroviral effects. we used a single cycle replicable (scr) h...

Phytochemical investigation of the aerial parts of Euphorbia erythradenia Bioss. (Euphorbiaceae), one of Iranian endemic Euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction was carried out. Five known triterpenes, including four cycloartanes and oleanolic acid, were isolated for the first time and identified using NMR and Mass techniques. Anti HIV...

Phytochemical investigation of the aerial parts of Euphorbia erythradenia Bioss. (Euphorbiaceae), one of Iranian endemic Euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction was carried out. Five known triterpenes, including four cycloartanes and oleanolic acid, were isolated for the first time and identified using NMR and Mass techniques. Anti HIV...

آقا صادقی, محمدرضا, اسعدی دالائی, سوگل, امیرمظفری, نور, حکمت, سهیلا, ذبیح الهی, رضوان, سادات, سید مهدی, سیادت, سید داور, فرهنگ اصفهانی, آذر,

Background and purpose: The need to find new antiviral compounds is increasing due to the emergence of resistant strains and toxicity of currently available HIV drugs. In this research the inhibitory activity of a number of novel iron chelating compounds derived from 3-Hydroxy-4-pyridinosnes was studied. Materials and methods: Single cycle replicable (SCR) virion was produced by transfection o...

Journal: :iranian journal of pharmaceutical research 0
abdul majid ayatollahi phytochemistry research center and school of pharmacy, shahid beheshti university of medical sciences, tehran, i.r. iran. seyed mohammad zarei department of pharmacognosy, school of pharmacy, shahid beheshti university of medical sciences, tehran, i.r. iran. arash memarnejadian department of hepatitis and aids, institute pasture of iran, tehran, i.r. iran. mustafa ghanadian department of pharmacognosy, isfahan faculty of pharmacy, isfahan university of medical sciences, isfahan, i.r. iran. mohammad heydarian moghadam department of audiology, school of rehabilitation, shahid beheshti university of medical sciences, tehran, i.r. iran. farzad kobarfard department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, i.r. iran.

phytochemical investigation of the aerial parts of euphorbia erythradenia bioss. (euphorbiaceae), one of iranian endemic euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction was carried out. five known triterpenes, including four cycloartanes and oleanolic acid, were isolated for the first time and identified using nmr and mass techniques. anti hiv...

Arash Memarnejadian, Mahdieh Soezi, Mohammad Reza Aghasadeghi, Rezvan Zabihollahi, Saeed Aminzadeh, Safieh Amini, Seyed Mehdi Sadat, Soheila Hekmat,

Background: The rapid increase of HIV-1 strains resistant to current antiretroviral drugs is a challenge for successful AIDS therapy. This necessitates the development of novel drugs, and to this end, availability of screening systems for in vitro drug discovery is a priority. Herein, we report the modification of a previously developed system for increased sensitivity, ease of use, and cost-ef...

Journal: :reports of biochemistry and molecular biology 0
mahdieh soezi hepatitis and aids department, pasteur institute of iran, tehran, iran - national institute of genetic engineering and biotechnology, tehran, iran arash memarnejadian tel: +98 21 66969291; fax: +98 21 66969291 saeed aminzadeh rezvan zabihollahi hepatitis and aids department, pasteur institute of iran, tehran, iran seyed mehdi sadat hepatitis and aids department, pasteur institute of iran, tehran, iran safieh amini hepatitis and aids department, pasteur institute of iran, tehran, iran

background: the rapid increase of hiv-1 strains resistant to current antiretroviral drugs is a challenge for successful aids therapy. this necessitates the development of novel drugs, and to this end, availability of screening systems for in vitro drug discovery is a priority. herein, we report the modification of a previously developed system for increased sensitivity, ease of use, and cost-ef...

2016
Abdul Majid Ayatollahi Seyed Mohammad Zarei Arash Memarnejadian Mustafa Ghanadian Mohammad Heydarian Moghadam Farzad Kobarfard

Phytochemical investigation of the aerial parts of Euphorbia erythradenia Bioss. (Euphorbiaceae), one of Iranian endemic Euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction was carried out. Five known triterpenes, including four cycloartanes and oleanolic acid, were isolated for the first time and identified using NMR and Mass techniques. Anti HIV...

آقاصادقی, محمدرضا, جوادی, فوزیه, ذبیح الهی, رضوان, رضایی, عباس, سادات, سیدمهدی, سیادت, سیدداور, وهاب پور, روح اله, پریور, کاظم,

زمینه و هدف : ویروس نقص ایمنی انسان (HIV) از خانواده رتروویریده و عامل سندرم نقص ایمنی اکتسابی (AIDS) می‌باشد. تهدیدی که عفونت HIV برای نظام سلامت جهانی ایجاد کرده؛ باعث شده است که مطالعه برای دستیابی به ترکیبات ضدویروسی جدید و همچنین طراحی و تولید واکسن HIV اهمیت ویژه‌ای پیدا کند. این مطالعه به منظور ساخت ویریون‌های HIV با توان یک سیکل همانندسازی با نام (Single Cycle Replicable) با استفاده از ...

ژورنال: :مجله علمی دانشگاه علوم پزشکی گرگان 0
سیدمهدی سادات sadat sm (msc) رضوان ذبیح الهی zabihollahi r (md) روح اله وهاب پور vahabpour r (msc) سیدداور سیادت siadat sd (phd) فوزیه جوادی javadi f (msc) عباس رضایی rezaei a (md) کاظم پریور

زمینه و هدف : ویروس نقص ایمنی انسان (hiv) از خانواده رتروویریده و عامل سندرم نقص ایمنی اکتسابی (aids) می باشد. تهدیدی که عفونت hiv برای نظام سلامت جهانی ایجاد کرده؛ باعث شده است که مطالعه برای دستیابی به ترکیبات ضدویروسی جدید و همچنین طراحی و تولید واکسن hiv اهمیت ویژه ای پیدا کند. این مطالعه به منظور ساخت ویریون های hiv با توان یک سیکل همانندسازی با نام (single cycle replicable) با استفاده از ...

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