نتایج جستجو برای: single cycle replicable virion scr
تعداد نتایج: 1135219 فیلتر نتایج به سال:
human immunodeficiency virus (hiv) infection is the major problem in the world. nowadays, new anti-retroviral drugs are extracted from medicinal plants, make an important role to supersede synthetic drugs with different side effects. in this study, we studied the salix aegyptiaca l extract, iranian herb, as an anti-hiv drug with anti-retroviral effects. we used a single cycle replicable (scr) h...
Phytochemical investigation of the aerial parts of Euphorbia erythradenia Bioss. (Euphorbiaceae), one of Iranian endemic Euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction was carried out. Five known triterpenes, including four cycloartanes and oleanolic acid, were isolated for the first time and identified using NMR and Mass techniques. Anti HIV...
Phytochemical investigation of the aerial parts of Euphorbia erythradenia Bioss. (Euphorbiaceae), one of Iranian endemic Euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction was carried out. Five known triterpenes, including four cycloartanes and oleanolic acid, were isolated for the first time and identified using NMR and Mass techniques. Anti HIV...
Background and purpose: The need to find new antiviral compounds is increasing due to the emergence of resistant strains and toxicity of currently available HIV drugs. In this research the inhibitory activity of a number of novel iron chelating compounds derived from 3-Hydroxy-4-pyridinosnes was studied. Materials and methods: Single cycle replicable (SCR) virion was produced by transfection o...
phytochemical investigation of the aerial parts of euphorbia erythradenia bioss. (euphorbiaceae), one of iranian endemic euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction was carried out. five known triterpenes, including four cycloartanes and oleanolic acid, were isolated for the first time and identified using nmr and mass techniques. anti hiv...
Background: The rapid increase of HIV-1 strains resistant to current antiretroviral drugs is a challenge for successful AIDS therapy. This necessitates the development of novel drugs, and to this end, availability of screening systems for in vitro drug discovery is a priority. Herein, we report the modification of a previously developed system for increased sensitivity, ease of use, and cost-ef...
background: the rapid increase of hiv-1 strains resistant to current antiretroviral drugs is a challenge for successful aids therapy. this necessitates the development of novel drugs, and to this end, availability of screening systems for in vitro drug discovery is a priority. herein, we report the modification of a previously developed system for increased sensitivity, ease of use, and cost-ef...
Phytochemical investigation of the aerial parts of Euphorbia erythradenia Bioss. (Euphorbiaceae), one of Iranian endemic Euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction was carried out. Five known triterpenes, including four cycloartanes and oleanolic acid, were isolated for the first time and identified using NMR and Mass techniques. Anti HIV...
زمینه و هدف : ویروس نقص ایمنی انسان (HIV) از خانواده رتروویریده و عامل سندرم نقص ایمنی اکتسابی (AIDS) میباشد. تهدیدی که عفونت HIV برای نظام سلامت جهانی ایجاد کرده؛ باعث شده است که مطالعه برای دستیابی به ترکیبات ضدویروسی جدید و همچنین طراحی و تولید واکسن HIV اهمیت ویژهای پیدا کند. این مطالعه به منظور ساخت ویریونهای HIV با توان یک سیکل همانندسازی با نام (Single Cycle Replicable) با استفاده از ...
زمینه و هدف : ویروس نقص ایمنی انسان (hiv) از خانواده رتروویریده و عامل سندرم نقص ایمنی اکتسابی (aids) می باشد. تهدیدی که عفونت hiv برای نظام سلامت جهانی ایجاد کرده؛ باعث شده است که مطالعه برای دستیابی به ترکیبات ضدویروسی جدید و همچنین طراحی و تولید واکسن hiv اهمیت ویژه ای پیدا کند. این مطالعه به منظور ساخت ویریون های hiv با توان یک سیکل همانندسازی با نام (single cycle replicable) با استفاده از ...
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