The genome of a herpesvirus highly pathogenic to rabbits, leporid herpesvirus 4 (LHV-4), was analyzed using high-throughput DNA sequencing technology and primer walking. The assembled DNA sequences were further verified by restriction endonuclease digestion and Southern blot analyses. The total length of the LHV-4 genome was determined to be about 124 kb. Genes encoded in the LHV-4 genome are m...

background: herpes virus group can persist in the latent form in the body, pneumocystis jerovecii, on the other hand, is a fungus which is ubiquitous in the respiratory tract of mammals, with 90% of adult human beings possessing antibodies to this organism. concomitant presence of different microorganisms, may result in one microorganism altering the activity of another. objectives: to determin...

Periodontitis is a multilayered factors disease with diverse clinical features not precisely explained by the etiologic role of bacteria. Herpesviruses have been found in periodontally affected sites by PCR. Herpesviruses are known to exert immune regulation and thus, variations on inflammatory and immune responses attributed to them may reduce host resistance against subgingival colonization a...

Long-term Safety of Topical Pimecrolimus and Topical Tacrolimus in Atopic Blepharoconjunctivitis Atopic blepharoconjunctivitis (ABC) is an ocular manifestation of atopy with a course similar to that of atopic dermatitis: chronic with exacerbations. Topical corticosteroids are widely used for ABC, but longtermuse has awell-established risk of adverse effects: increase of intraocular pressure (IO...

objectives: regarding the implication of viruses particularly herpes in pemphigus vulgaris, we sought to assess and compare the level of immunoglobulin g (igg) antibodies against herpes simplex virus types 1 and 2 (hsv1 and hsv2), cytomegalovirus (cmv) and epstein-barr virus (ebv) in patients with pemphigus vulgaris and healthy people.     materials and methods: in this cross-sectional study, 2...

Abstract Viruses closely related to human pathogens can reveal the origins of infectious diseases. Human herpes simplexvirus type 1 (HSV-1) and 2 (HSV-2) are hypothesized have arisen via host-virus codivergence cross-species transmission. We report discovery novel simplexviruses during a large-scale screening fecal samples from wild gorillas, bonobos, chimpanzees. Phylogenetic analysis indicate...

Based on an ethnobotanical survey related to inflammatory diseases, 67Guinean plant species belonging to 35 botanical families were inventoried. Some plant species frequently used in the treatment of rheumatism, skin diseases and microbial infections were selected and submitted to a biological investigation including antimicrobial and anticomplement activities. At a concentration of 1mg/ml, all...