chewable ferrous fumarate tablet is the best iron dosage form for children due to better compliance and lower teeth staining compared to the oral drop. because of the different desirable properties of chewable tablets and the opposing effects of fillers on them, the mathematical experimental design was used as the formulation approach. different series of formulations based on single filler (la...

the purpose of this research was to prepare a floating matrix tablet containing domperidone as a model drug. polyethylene oxide (peo) and hydroxypropyl methylcellulose (hpmc) were evaluated for matrix-forming properties. a simplex lattice design was applied to systemically optimize the drug release profile. the amounts of peo wsr 303, hpmc k15m and sodium bicarbonate were selected as independen...

The purpose of this research was to prepare a floating matrix tablet containing domperidone as a model drug. Polyethylene oxide (PEO) and hydroxypropyl methylcellulose (HPMC) were evaluated for matrix-forming properties. A simplex lattice design was applied to systemically optimize the drug release profile. The amounts of PEO WSR 303, HPMC K15M and sodium bicarbonate were selected as independen...

The purpose of this research was to prepare a floating matrix tablet containing domperidone as a model drug. Polyethylene oxide (PEO) and hydroxypropyl methylcellulose (HPMC) were evaluated for matrix-forming properties. A simplex lattice design was applied to systemically optimize the drug release profile. The amounts of PEO WSR 303, HPMC K15M and sodium bicarbonate were selected as independen...

The aim of the present study was to prepare floating matrix tablet glipizide by applying Simplex lattice design using kappa carrageenan, Hydroxypropylmethylcellulose K15M and sodium bicarbonate as independent variable. similarity factor (f2), time release 50 % drug 90 were taken dependent factors. A total 14 batches prepared given Design-Expert® Software (version- 9.0.6, Stat-Ease) response obt...

In this paper, (d + 1)-pencil lattices on simplicial partitions in Rd are studied. The barycentric approach naturally extends the lattice from a simplex to a simplicial partition, providing a continuous piecewise polynomial interpolant over the extended lattice. The number of degrees of freedom is equal to the number of vertices of the simplicial partition. The constructive proof of this fact l...

A k-dimensional lattice simplex σ ⊆ Rd is the convex hull of k + 1 affinely independent integer points. General lattice polytopes are obtained by taking convex hulls of arbitrary finite subsets of Zd . A lattice simplex or polytope is called empty if it intersects the lattice Zd only at its vertices. (Such polytopes are studied also under the names elementary and latticefree.) In dimensions d >...

SNEDDS merupakan campuran isotropik yang terdiri dari obat, surfaktan, ko-surfaktan dan minyak. Pengembangan optimasi formulasi tepat diperlukan untuk meminimalisir waktu, biaya, serta menjamin optimal. Tujuan penulisan artikel ini adalah menjelaskan aplikasi simplex lattice design (SLD) box behnken (BBD) dalam SNEDDS. Metode digunakan menyusun review yaitu teknik studi pustaka dengan mencari l...

For a minimal inequality derived from a maximal lattice-free simplicial polytope in R, we investigate the region where minimal liftings are uniquely defined, and we characterize when this region covers R. We then use this characterization to show that a minimal inequality derived from a maximal lattice-free simplex in R with exactly one lattice point in the relative interior of each facet has a...