Tricalcium silicate cements have been successfully employed in the biomedical field as bioactive bone and dentin substitutes, with widely acclaimed osteoactive properties. This research analyzed the effects of different tricalcium silicate cement formulations on the temporal osteoactivity profile of human bone marrow-derived mesenchymal stem cells (hMW-MSCs). These cells were exposed to four co...

The compositions and molecular structures of anhydrous and hydrated cements are established by using advanced solid-state nuclear magnetic resonance (NMR) spectroscopy methods to distinguish among different molecular species and changes that occur as a result of cement hydration and setting. One- and two-dimensional (2D) solid-state (29)Si and (27)Al magic-angle spinning NMR methodologies, incl...

One of the most revolutionary materials introduced in Endodontics was the Mineral Trioxide Aggregate (MTA). The investigations regarding MTA formulation allowed researchers to disclose the composition and also some clinical problems related to the clinical application of this material. The augmentation on MTA’s studies resulted in the development a new generation of Endodontic materials, the ca...

PURPOSE Calcium-silicate cements have been recently proposed for application in dentistry as root-end filling and root-perforation repair materials. The aim of this study was to investigate the effect of ageing of experimental calcium-silicate cements on the chemistry, morphology and in vitro bioactivity of the surface, as well as on osteoblast viability and proliferation. METHODS Two experim...

Calcium silicate-based materials (also called MTA) are increasingly being used in endodontic applications. However, the handling properties of MTA are not optimal when it comes to injectability and cohesion. Premixing the cements using glycerol avoids these issues. However, there is a lack of data on the effect of common cement variables on important properties of premixed cements for endodonti...

INTRODUCTION On the basis of many clinical observations, some calcium silicate-based cements have a high potential for staining tooth tissue. This feature greatly limits the use of those cements, particularly for anterior teeth. This review aimed to provide a systematic evaluation of published in vitro studies to determine the effect of different calcium silicate-based cements on dental tissue ...

Early tooth-colored restorative materials were weak and only suitable for anterior teeth. Over time, composites were developed that offered improved properties enabling their use in posterior teeth where subject to occlusal loading and forces of mastication. Secondary caries is the main reason for failure of both amalgam and composite restorations. Amalgam restorations offer ease-of-use but poo...

Early tooth-colored restorative materials were weak and only suitable for anterior teeth. Over time, composites were developed that offered improved properties enabling their use in posterior teeth where subject to occlusal loading and forces of mastication. Secondary caries is the main reason for failure of both amalgam and composite restorations. Amalgam restorations offer ease-of-use but poo...

Objective. The aim of this study was to evaluate the physicochemical properties and bioactivity of two formulations of calcium silicate-based cements containing additives (CSCM) or resin (CSCR), associated with radiopacifying agents zirconium oxide (ZrO2) and niobium oxide (Nb2O5) as micro- and nanoparticles; calcium tungstate (CaWO4); and bismuth oxide (Bi2O3). MTA Angelus was used as control....