نتایج جستجو برای: signaling molecules

تعداد نتایج: 471054  

Journal: :jentashapir journal of health research 0
torello lotti department of dermatology, university of rome “guglielmo marconi”, rome, italy; institute of dermatology lifecronos, florence, italy; world health academy foundation, zurich, switzerland; department of dermatology, university of rome “guglielmo marconi”, rome, italy. tel: +39-3286214588, fax: +39-0637725647 tatiana rivkina private practitioner, rome, italy massimo fioranelli physiology department, university b.i.s., group of institutions, punjab technical university, punjab, india

scientific evidence regarding the efficacy and safety of the ldm approach in the treatment of psoriasis vulgaris, and positive preliminary data regarding the oral administration of low dose activated cytokines for vitiligo and atopic dermatitis treatment, support the ldm-based therapeutic approach for many dermatological diseases. ldm suggests the use of low-doses of activated biological molecu...

 Primordial Germ Cells (PGCs) are unipotent precursors of the gametes. PGCs can give rise to a type of pluripotent stem cells in vitro that are called embryonic germ (EG) cells. PGCs can also acquire such pluripotency in vivo and generate teratomas. Under specific culture conditions, PGCs can be reprogrammed to embryonic germ cells which are capable of expression of key pluripotency marker...

ژورنال: پوست و زیبایی 2013
تبریزی, مینا, رئوفیان, رضا, غلامعلی, فاطمه, نورمحمدپور, پدرام, هاشم‌زاده‌چالشتوری, مرتضی, وندرجب‌پور, فاطمه,

Basal cell carcinoma (BCC) is the most common cancer in Iran and in the world and its prevalence may become equivalent to the prevalence of all other cancers combined in the future. The Hedgehog (Hh) signaling pathway has an important role in tumorigenesis of BCC. Mutations in PTCH and Smo molecules of this pathway account for 85% to 95% of sporadic BCCs and also most cases of inherited cases. ...

Objective(s): Chronic myeloid leukemia (CML) is a myeloid clonal proliferation disease defining by the presence of the Philadelphia chromosome that shows the movement of BCR-ABL1. In this study, the critical role of the Musashi2-Numb axis in determining cell fate and relationship of the axis to important signaling pathways such as Hedgehog and Notch that are essential ...

Journal: :Journal of Thoracic Oncology 2009

Journal: :iranian journal of diabetes and obesity 0
mohammad hasan sheikhha md, phd in medical molecular genetics, yazd diabetes research center, shahid sadoughi university of medical sciences, yazd, iran. eskandar taghizadeh msc in human genetics, genetics department, shahid sadoughi university of medical sciences, yazd, iran. mohammad bagher mahmoodi msc in human genetics, genetics department, shahid sadoughi university of medical sciences, yazd, iran. seyed mehdi kalantar phd in cytogenetic, research and clinical center for infertility, shahid sadoughi university of medical sciences, yazd, iran.

single-gene disorders occur when mutation in a gene causing alteration of gene function while in multifactorial disorders, mutations occur in multiple genes, and these are usually coupled with environmental causes. in addition, in a multifactorial disorder such as diabetes, the complication is under the influence of different genes. for example, in diabetic retinopathy many genes are involved i...

Eskandar Taghizadeh, Mohammad Bagher Mahmoodi, Mohammad Hasan Sheikhha, Seyed Mehdi Kalantar,

Single-gene disorders occur when mutation in a gene causing alteration of gene function while in multifactorial disorders, mutations occur in multiple genes, and these are usually coupled with environmental causes. In addition, in a multifactorial disorder such as diabetes, the complication is under the influence of different genes. For example, in diabetic retinopathy many genes are involved i...

Arabinogalactan proteins (AGP) are a class of cell surface plant peptidoglycans which have been implicated in root elongation and signal transduction pathways. AGPs function not only as markers of cellular identity but also as signaling molecules, which might initiate signal transduction. Aluminum promotes the elongation of tea (Camellia sinensis L.) roots. Although some mechanisms by which Al ...

Several signaling pathways and transcription factors control the cell fate in its in vitro development and differentiation. The orchestrated use of these factors results in cell specification. In coculture methods, many of these factors secrete from host cells but control the process. Today, transcription factors required for retinal progenitor cells are well known, but the generation of these ...

Journal: :iranian journal of allergy, asthma and immunology 0
homa davoodi golestan university of medical sciences, gorgan, iran seyed reza hashemi faculty of animal sciences, gorgan university of agricultural sciences and natural resources, gorgan, iran heng fong seow department of pathology, immunology unit, universiti putra malaysia, 43400 serdang selangor, malaysia

toll-like receptor 4 (tlr4), considered one of  the most important tlr, recognizes lipopolysaccharide of  gram-negative bacteria. recognition  of  ligands by  tlrs  induces signaling pathways resulting in activation of transcriptional factors such as nf-κb which are involved in  the  expression of  inflammatory cytokines and  chemokines. to  prevent  an inappropriate immune response, a complex ...

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