ferula communis l., subsp. communis, namely giant fennel, has extensively been used in traditional medicine for a wide range of ailments. fresh plant materials, crude extracts and isolated components of f. communis showed a wide spectrum of in vitro and in vivo pharmacological properties including antidiabetic, antimicrobial, antiproliferative, and cytotoxic activities. the present paper, revie...

ISSN: 2410-8790 Asif, M., / Current Science Perspectives 1(3) (2015) 77-90 www.iscientic.org www.bosaljournals/csp/ 78 [email protected] on the traditional knowledge of medicinal plant use (Cox 1994). These compounds have made many plants useful also for humans for instance as spices, medicines etc. Natural coumarins, like other unsaturated lactones, may exert various effects on livin...

Coumarins are natural plant products that have been the subject of extensive phytochemical and pharmacological research studies in the past few decades. The core structure of coumarins is derived from the respective cinnamates via ortho-hydroxylation of the aromatic ring, trans/cis isomerization, and lactonization. Various substitution patterns of coumarins have been reported, whereas the biosy...

Coumarins are natural polyphenol lactones comprising of fused rings of benzene and α-pyrone. The current study demonstrates the inhibitory effect of coumarins with various substitutions on Mycobacterium smegmatis mc2 155. We also demonstrate the effect of pomegranate (Punica granatum) extract containing ellagic acid, on M. smegmatis as well as their affect on MtbFtsZ (FtsZ from Mycobacterium tu...

Fluorescence emission after two-photon absorption of coumarins and xanthenes in an alcoholic solution was measured in the tuning range of a femtosecond-pulsed titanium-sapphire laser (750-840 nm). Xanthenes, which have a low one-photon absorption in the near UV, show a higher fluorescence signal after two-photon absorption than the UV-excitable coumarins. When fluxes of 10(28) photons/(cm(2) s)...

Coumarins are classified as a member of the benzopyrone family. all of which consist of a benzene ring joined to a pyrone ring. The benzopyrones can be subdivided into the benzoalfa-pyrones to which the coumarins belong and the benzo-gama-pyrones, of which the flavonoids are principal members. Umbelliferone, esculetin and scopoletin are the most widespread coumarins in nature. During the synthe...

Pd-catalyzed oxidative Heck reactions of coumarins were developed via simultaneous C-H functionalization at the C3 position of coumarins under aerobic conditions.

1. Abstract 2. Introduction 3. Phytoalexins and cancer prevention mechanisms 3.1. Antimicrobial activity 3.2. Proliferation 3.2.1. Cruciferous phytoalexins 3.2.2. Deoxyanthocyanidins 3.2.3. Glycoalkaloids 3.2.4. Stilbenes 3.2.5. Phenolic coumarins and garlic phytoalexins 3.3. Apoptosis 3.3.1. Stilbenes 3.3.2. Phenolic coumarins 3.3.3. Glycoalkaloids 3.3.4. Garlic phytoalexins 3.3.5. Di-terpenes...

Ferula communis L., subsp. communis, namely giant fennel, has extensively been used in traditional medicine for a wide range of ailments. Fresh plant materials, crude extracts and isolated components of F. communis showed a wide spectrum of in vitro and in vivo pharmacological properties including antidiabetic, antimicrobial, antiproliferative, and cytotoxic activities. The present paper, revie...

Coumarins are one of the most important classes of heterocycles that occupies prime position in synthetic and pharmaceutical chemistry due to their diverse applications. Broad spectrum of biological activity and their utility as useful synthons, coumarins have attracted researchers to work on this moiety, which is instrumental in the development of coumarin chemistry. This review article provid...