introduction and aims: tt virus (ttv) is a dna virus and is proposed as a potential cause of non-a to e hepatitis. we aimed to investigate, for the first time, the prevalence of ttv in iranian healthy blood donors. materials and methods: three hundred and twelve healthy iranian blood donors were randomly selected and tested for ttv dna by the seminested polymerase chain reaction method. serum a...

BACKGROUND Evidence suggests that the predictive value of serum alanine aminotransferase (ALT) levels for prognosis, measured by indices such as all-cause mortality and medical costs, may be modified by body mass index (BMI). However, the relationship between serum ALT and BMI has not been satisfactorily elucidated. METHODS Four thousand, five hundred and twenty-four community dwelling Japane...

Alanine aminotransaminase (ALT), is an enzyme that normally resides in serum and body tissues, especially in the liver. It is released into the serum as a result of tissue injury; hence the concentration of ALT in the serum may be increased with acute damage to hepatic cells. A single use, disposable biosensor, comprising iridium nano-particle as catalyst dispersed on carbon paste, has been dev...

Serum alanine aminotransferase (ALT) concentration is the most commonly used marker for hepatocellular injury. We investigated the suitable cutoff value of serum ALT for the diagnosis or prediction of fatty liver. In 1578 Japanese adults (1208 men, 370 women; 35-69 years of age) who visited our center both in 2000 and between April 2007 and March 2008 (2007-2008), serum ALT concentration was an...

BACKGROUND Current guidelines introduce periodic monitoring of serum alanine transaminase (ALT) as the first-line modality in follow-up patients, with a hepatitis B virus (HBV) inactive carrier state. OBJECTIVES This study aimed to determine the incidence rate and patterns of ALT fluctuations and prognostic values for the development of chronic HBV e antigen (HBeAg)-negative hepatitis B (CHB)...

BACKGROUND The efficacy of serum alanine aminotransferase (ALT) levels in predicting the severity of hepatitis C virus (HCV) infection is unclear. OBJECTIVE To compare histologic scoring of liver pathology in patients with chronic HCV infection with normal or elevated serum ALT. METHODS Liver biopsies were performed in patients with HCV infection and either normal (n=40) or elevated (n=76) ...

BACKGROUND To investigate whether serum alanine aminotransferase (ALT) levels within normal range were associated with augmentation index (AIx) and cardiometabolic risk factors in nondrinkers and drinkers in Chinese community-dwelling population. METHODS There were 4165 participants with serum ALT levels within normal range. RESULTS Alcohol drinking was observed in 1173 participants (28.2%)...

background: among most of the hepatic diseases, elevation of alanine amino transferase (alt) level is the hallmark of hepatocyte necrosis. but, no study has been performed in this field in iran. materials and methods: this study is designed to compare the grade, stage, and histological activity index (hai score) of liver pathology between patients with normal serum alt and elevated serum alt. i...

BACKGROUND Few studies have investigated the relationship between carotid-femoral pulse wave velocity (cfPWV) and serum alanine aminotransferase (ALT) normal-range levels across the world. The current analysis was designed to explore the relationship of serum ALT normal-range levels to cfPWV and metabolic syndrome (Mets) in non-drinkers and drinkers in a Chinese community-dwelling population. ...

PURPOSE Elevation in serum alanine aminotransferase (ALT) levels is a biomarker for metabolic syndrome (MS); however, the relationship has not been fully investigated within the reference interval of ALT levels. Our objective was to explore the relationship between serum ALT levels within the reference interval and MS in Chinese adults. MATERIALS AND METHODS This cross-sectional study include...