brucellosis is an endemic disease in our country. neurobrucellosis occurs in 5 to 10% of cases, and can present at any stage of of the disease. this study was undertaken to evaluate clinical, epidemiological and paraclinical aspects of brucellosis with and without neurological manifestations. data of 30 patients, 15 cases with nervous system involvement (neurobrucellosis) and 15 cases without n...

The test serum for detecting the Rh antigen in the red cells of the human population may be prepared according to the technique originally described by Landsteiner and Weiner (1941) by the injection of red cells from the Rhesus monkey into . guinea-pigs or rabbits. As in other immunological experiments, only a few of the animals thus treated yield a satisfactory anti-serum. Even then, the actio...

A 57-year-old man with rheumatoid arthritis developed severe anemia during treatment with adalimumab plus methotrexate. Cold agglutinin disease was diagnosed because haptoglobin was undetectable, cold agglutinin was positive (1 : 2048), and the direct Coombs test was positive (only to complement). Although the cold agglutinin titer was normalized (1 : 64) after treatment with prednisolone (0.7 ...

typhoid fever is endemic in iran. isolation of s. typhi is a gold standard for diagnosis. laboratory diagnosis of s. typhi infection relies on serological tests such as the widal test. this study describes seroprevalence of to and th antibody in nonfebrile healthy and febrile with non-typhoid illness. for detection of sensitivity and specificity of widal test in typhoidal fever diagnosing widal...

The association of antibody with y-globulins was first demonstrated electrophoretically in the serum of rabbits immunized with egg albumin; Tiselius & Kabat (1939) and Enders (1944) found antibodies against a wide range of virus, toxin and bacterial antigens in the y-globulin prepared from pooled human plasma by ethanol precipitation. Kekwick & Mackay (1954) used one of these antibodies, the Sa...

Many serological techniques have been developed to aid in the discrimination of significant candidiasis from other clinical states. Serum anti-candida precipitin and agglutinin quantification by counterimmunoelectrophoresis and latex agglutination were statistically evaluated as to their respective ability to accomplish this discrimination. Forty-five serum specimens from 16 patients with docum...

Serum and tissues containing agglutinin for the hog cholera bacillus may be dried in vacuo over sulfuric acid without appreciably injuring the antibody. The desiccated material when extracted with appropriate amounts of distilled water offers a basis for accurate comparison of antibody content. The greatest concentration of agglutinin occurred in the liver, provided the animals injected with sm...

In the serum of S-negative secundi para woman a specific anti-S agglutinin of the IgG type was identified. The same agglutinin was identified in the serum and on the eritrocytes of the newborn with sympthomes of a light Hemolytic disease. Exchange transfusion was not necessary. The anti-S described is an immune warm agglutinin showing the efect of dose and is discovered only by the Coombs techn...

It is possible by means of curves to depict graphically the behavior of the various antibodies under various conditions. Logarithmic curves based on the data presented in the tables are submitted in Text-fig. 1. In general it is evident that antibody destruction goes on gradually as the temperature is increased. Thus 65 degrees C. for 20 minutes diminishes the activity of all the antibodies wit...