Neonates exposed at term to selective serotonine (SSRI) or serotonine-norepinephrine reuptake inhibitors (SNRI) medications may encounter symptoms such as irritability, rigidity, tremor and respiratory distress. Most available data suggest that these self limited symptoms are due to discontinuation of the drug, although there are documented cases of symptoms associated with high serum concentra...

OBJECTIVE Role of the atelectasis (hypoxia) in the respiratory system of the live and exited newborn (250 up to 3000 g. of body weight), which has died due to different causes was studied in this work. METHODS Response of tracheal rings to dopamine, serotonine and ethanol in the different molar concentrations (dopamine: 0.05 mg/ml, 0.5 mg/ml, 5 mg/ml; serotonine (5-HT): 10(-4), 10(-3), 10(-2)...

Post-traumatic stress disorder (PTSD) frequently occurs in commorbidity with different mental disorders, including suicidal behaviour. Group of biological factors, including serotonergic system, HPA axis and some genetic factors, are being studied as potential markers, able to differentiate suicidal and non-suicidal behaviour across the group of PTSD patients. This study is examining statistica...

Abbreviations: A1R: Adenosine A1 Receptor; A2AR: Adenosine A2A Receptor; A2BR: Adenosine A2B Receptor; A3R: Adenosine A3 Receptor; Cpd: Compound; D2R: Dopamine D2 Receptor; Emax: Efficacy; gp: Guinea-pig; GPCR: G-Protein Coupled Receptor; h: Human; H1R: Histamine H1 Receptor; H3R: Histamine H3 Receptor; r: rat; 5-HT1AR: Serotonine 5-HT1A Receptor; βR: β-Adrenergic Receptors; β2R: Adrenergic β2 ...

BACKGROUND Unless metastatic or compressing the pancreatic duct, carcinoid of the pancreas are asymptomatic showing normal levels of serotonine and its metabolites in plasma and urine, thus resulting in delayed diagnosis and a consequent poor prognosis. However, if resection is timely accomplished, no local recurrence might be encountered and a normal survival might be expected in the absence o...

traditionally, schizophrenia was considered to be a severe psychiatric disorder, with a chronic course and an unfavorable outcome. throughout history, there has been incidence of schizophrenia, roughly one percent of the population, consistently, in every culture. it is generally acknowledged that schizophrenia has multifactorial etiology, with multiple susceptibility genes interacting with env...

A study of the association of serotonine with 5'-AMP by PMR spectroscopy is described. The association constants obtained from the chemical shift of non-equivalent protons show considerable variation outside experimental error, a fact which wTas reported by several authors. To support the suppositon that small amounts of complexes of different stoichiometry, — which in general can hardly be det...

BACKGROUND Many subjects with depression and with brain lesions can poorly control their emotions with fits of weeping and tearfulness; neurological patients present outbursts of laughter as well. This condition is called Emotional Lability (EL). The antidepressant drugs of the family of selective serotonine reuptake inhibitors (SSRI) improve EL within a few days in both depressive and neurolog...

spectrophotometric and electrochemical studies were successfully used in quantitative analysis of amitriptyline hydrochloride (ath) and nortriptyline hydrochloride (nth). conductometric titration were carried out in equeous solution using iodide and dopamine and serotonine as titrant. two new methods using spectrophotometry are dascribed for the determination of (ath) and (nth) with potassium b...