bacterial meningitis is still the leading cause of high morbidity and mortality among the children. the present study was conducted to determine the epidemiology, clinical characteristics of bacterial meningitis and to evaluate the risk factors associated with developing the infection.this cross sectional study was conducted in three hospitals of gaza strip -palestine during the period 2009. al...

objective due to the high prevalence of syndrome of inappropriate antidiuretic hormone secretion (siadh). this study was carried out to evaluate the prevalence and relevant parameters of siadh in children with septic and aseptic memingitis hospitalized at kashan shahid beheshti hospital between 1996 and 2006. materials & methods this descriptive study was conducted on 230 patients with meningit...

Background: Analysis of biofluids provides a unique window into the biochemical status of a living organism since the composition of a given biofluid will be modulated according to the level of function of the cells that are intimately concerned with its manufacture and secretion. One of the most successful approaches to biofluid analysis has been the application of NMR spectroscopy. Objective...

Septic cavernous sinus thrombosis is a rare clinical condition. Although Staphylococcus aureus is the most common pathogen causing septic cavernous sinus thrombosis [CST], it is an uncommon cause of meningitis. We report the first case of CST with meningitis in Hyderabad, Andhra Pradesh, caused by community acquired epidemic strain of Methicillin resistant staphylococcus aureus [MRSA], in a pre...

We examined the compartmentalization of bioactive tumour necrosis factor (TNF) and interleukin 6 (IL-6) to the subarachnoid space and systemic circulation in patients with meningococcal meningitis and septic shock/bacteraemia. In patients with meningitis, median levels of TNF in 31 paired samples of cerebrospinal fluid (CSF) and serum were respectively 783 pg/ml and below detection limit (p < 0...

BACKGROUND Meningitis caused by Neisseria meningitidis is primarily a disease of children and young adults. If septic shock complicates the course of meningitis, it must be treated in the intensive care unit. CASE REPORT An 18 year-old man with symptoms of meningococcal meningitis and clinical features of septic shock was admitted to the ICU. Tachycardia (heart rate 140 min⁻¹) required v...

BackgroundRapid initiation of antibiotic treatment is considered crucial in patients with severe infections such as septic shock and bacterial meningitis, but may not be important for other infectious syndromes. A better understanding which can tolerate a delay start therapy stewardship purposes.ObjectivesTo explore the existing evidence on impact time to antibiotics clinical outcomes presentin...

was hopeless. Where the infection is diffuse the prognosis is still very bad. But we have learnt that if in the earliest stage, when the trouble is still, we hope, circumscribed, we can remove the infective focus, the patient's chances of recovery are by no means poor. This emphasises the importance of deciding, quite at the beginning of any case of meningitis, whether an otorrhoea may be the f...