background sepsis can be defined as the body’s response to an infection. sepsis in children remains a significant cause of morbidity and mortality worldwide. objectives this study focuses on the etiological factors, risk factors, and clinical characteristics of sepsis in neonate and pediatric patients. patients and methods a prospective study was conducted over a six-month period in the pediatr...

sepsis is the systemic response to severe infection in critically ill patients. sepsis, septic syndrome & septic shock represent the increasingly severe stages of the same disease. despite the remarkable improvements in outcome, sepsis & septic shock remain an important cause of morbidity & mortality in children. this is a retrospective study among the patients who were admitted in the pediatri...

procalcitonin (pct) is a precursor peptide for the hormone calcitonin and is frequently increased in overt sepsis. the aim of this study was to test diagnostic accuracy of procalcitonin among patients with positive systemic inflammatory response syndrome (sirs) in identifying sepsis. in this cross sectional study, from 563 patients with positive sirs admitted through the emergency department of...

sepsis constitutes an important cause of hospital admission with a high mortality rate. appropriate antibiotic therapy is the cornerstone of therapy in patients with sepsis. although numerous studies have recommended early antibiotic initiation in severe sepsis or septic shock stages of sepsis syndrome, its role in treatment of patients with sepsis who have not entered these stages remains to b...

background sepsis is one of the most important causes of morbidity and mortality in the intensive care units (icus). it is difficult to accurately differentiate sepsis from similar diseases rapidly. therefore, it becomes critical to identify any biomarker with the ability of differentiation between sepsis and nonsepsis conditions. the urokinase plasminogen activator receptor has been implicated...

Sepsis is associated with acute respiratory distress syndrome, which has a significant impact on the prognosis of patients. Several studies have shown that microbiota plays role in sepsisinduced but relationship between and syndrome not fully understood. We conducted case-control single-center study 19 sepsis-induced patients 36 sepsis-noninduced to investigate clinical features expression. The...

background procalcitonin (pct) levels are increased in sepsis. in most previously conducted research, pct levels were found to increase during septic shock. objectives the purpose of this study was to compare pct levels with crp and esr levels in children with systemic inflammatory response syndrome (sirs), sepsis, and septic shock. methods this cross-sectional study was conducted between decem...

background one of the main components involving in the pathogenesis and prognosis of sepsis and septic shock is natriuretic peptide. hemodynamic changes in sepsis or septic shock might explain increased plasma levels of these peptides circulations. objectives the present study aimed to assess the value of brain natriuretic peptide (bnp) in prediction of sepsis state and its related morbidity. w...

Severe sepsis has been known to trigger for takotsubo syndrome which is associated with profound physical or emotional stress. Severe sepsis is also associated with sepsis-induced cardiomyopathy, a reversible myocardial depression. We report a case in which a patient with takotsubo syndrome, cardiogenic shock, severe sepsis, and adult respiratory distress syndrome was managed with an Impella Ca...

Sepsis is a significant health problem, considering that, annually, over 20 million people fall ill from sepsis. Despite the development of medicine in recent decades, mortality rate sepsis exceptionally high (about 26%). The definition developed together with understanding mechanism At beginning 1990s, first was created, according to which defined as systemic inflammatory response syndrome (SI...