some formulations of drug in adhesive transdermal drug delivery systems ()tddss)( with different functional and non-functional acrylic pressure sensitive adhesives psas)( were prepared. for this purpose fentanyl was used as a drug component. the effects of psas type on skin permeation and in vitro drug release from devices were evaluated using hydrodynamically well-characterized chien permeatio...

background: strontium, zinc, and potassium salts have been demonstrated to inhibit irritation and infl ammation when applied topically. particularly, strontium chloride (sc) and potassium nitrate (kn) are reported to reduce skin and tooth sensitivity.the aim of the present study was to compare the anti-irritant eff ects of four inorganic salts and assign the ingredient which can suppress skin i...