background: complaining of tearing was found in some of our patients after phacoemulsification surgery for senile cataract. secondary acquired lacrimal drainage obstruction has been proposed to happen due to different causes. this study was performed at feiz hospital in isfahan, iran from september to december of 2004 to evaluate the effects of phacoemulsification surgery on tear drainage in ey...

The pathogenesis of cataract has been found to be influenced by a number of factors including oxidative stress. Catalase, glutathione peroxidase (GPX), and superoxide dismutase (SOD) are some of the antioxidant enzymes that protect the body from oxidative damage. The present study investigates the activities of erythrocyte catalase, GPX, and SOD with respect to senile cataract (non-diabetic cat...

PURPOSE To determine if the presence of certain polymorphisms in the DNA repair gene XPC and the apoptosis inductor gene p53 is associated with pre-senile cataract development. METHODS We have performed a retrospective study over three groups of patients. The group with pre-senile cataract formed by 72 patients younger than 55 with cataract surgery. The group with senile cataract formed by 10...

Many factors such as aging, changes in blood electrolytes levels, and possibly family history are involved in senile cataract formation. Changes in serum electrolytes levels can induce changes in aqueous electrolytes levels and effect on lens metabolism and probably cataract formation. In this paper, we study serum level of Na(+ )and K(+) in senile cataract patients and normal individuals. Meth...

Histone acetylation plays key roles in gene expression, but its effects on superoxide dismutase 1 (SOD1) expression in senile cataract remains unknown. To address this problem, the study was to investigate the influence of histone acetylation on SOD1 expression and its effects in the pathogenesis of senile cataract. Senile cataract was classified into three types-nuclear cataract (NC), cortical...

The activity of Cu,Zn superoxide dismutase in the fluid obtained from eye lens capsules after cataract surgery was investigated in samples obtained from patients with senile cataract and with senile cataract combined with diabetes mellitus. Two parameters were measured and compared: the frequency of occurrence of detected superoxide dismutase activity and the relative activity of the enzyme in ...

PURPOSE Glutathione S-transferase (GST) polymorphisms have been considered risk factors for the development of senile cataract. However, the results are not consistent. In this study, the authors conducted a meta-analysis to assess the association between GSTM1 and GSTT1 null genotypes and the risk for senile cataract. METHODS Published literature from PubMed, EMBASE, and other databases were...

purpose: to report and compare outcomes and intra- and postoperative complications of senile cataract surgery using phacoemulsification in patients with and without pseudoexfoliation syndrome. methods: consecutive patients with pseudoexfoliation syndrome who underwent phacoemulsification in one or both eyes for senile cataracts between october 2009 and october 2010 were enrolled in the study. i...