background: given the importance of the role of depression in predicting the outcome of cardiovascular disorders, current medications for treating depression, particularly selective serotonin reuptake inhibitors (ssris), are taken into  consideration. this study aimed to systematically review the published findings in the use of ssris and the risk for cardiac events. materials and methods: an i...

OBJECTIVE Medications commonly used to treat heart disease, anxiety, and depression can interact resulting in an increased risk of bleeding, warranting a cautious approach in medical decision making. This retrospective, descriptive study examined the prevalence and the factors associated with the use of both selective-serotonin reuptake inhibitor and platelet aggregation inhibitor among individ...

Results: Catalepsy duration was reduced by the non-selective noradrenaline and serotonin reuptake inhibitors imipramine and amitriptyline (21.1% and 22.3% reduction by 20 mg/kg imipramine and amitriptyline, respectively). Catalepsy duration was increased by the selective serotonin reuptake inhibitors (SSRIs) fluoxetine, fluvoxamine, and citalopram and by the serotonin receptor antagonist and re...

objective: hypoglycemia with multiple etiologies is a common in diabetic patients. the current study describes the probability of interaction between maprotiline, selective serotonine reuptake inhibitors like citalopram for induction of hypoglycemia. case presentation: a 47 year-old diabetic woman used tablet citalopram 20mg daily because of generalized anxiety disorder from two years ago, but ...

OBJECTIVES Prolongation of the QT interval is a risk factor for sudden death. Selective serotonin-reuptake inhibitor antidepressants can prolong the QT interval and are widely used by pregnant women. Whether antenatal exposure to selective serotonin-reuptake inhibitor causes QT prolongation in offspring is unknown. The aim of this study was to determine the effect of maternal use of selective s...

Czaja AS, Anderson HD, Ghosh D, Davidson J, Campbell JD, Valuck RJ. Increased Odds of Ventricular Arrhythmias Associated with Selective Serotonin Reuptake Inhibitor Use among the Pediatric and Young Adult Population: A Case-Control Study. J Pediatr 2020;226:173-8. Among children young adults, what is ventricular arrhythmia risk associated selective serotonin reuptake inhibitor (SSRI) use? Case–...

data on the effects of serotonin reuptake inhibitors on learning and memory processes are not consistent. in the present study, the effects of citalopram, a very potent and completely selective inhibitor of the serotonin reuptake on spatial discrimination in the t-maze and morris water maze, were assessed in mice and/or rats. animals received different doses of citalopram (1, 2, 4, 8 or 16 mg/k...

Abbreviations: CRH: Corticotropin Releasing Hormone; CRH1: Corticotropin Releasing Hormone Receptor; CSF: Cerebro Spinal Fluid; D2: Dopaminergic Subreceptor; GABA: Gamma Amino Butyric Acid; GABAA: Gamma-Aminobutyric Acid Subtype A Receptors; GABAB: Gamma-Aminobutyric Acid Subtype B Receptors; Gal2: Galanin 2; 5-HT: Serotonergic Receptor; 5-HT1A: 5-Hydroxytryptamine 1A Receptors; 5-HT7: 5-hydrox...