background: endometriosis, a common chronic inflammatory disorder, is defined by the atypical growth of endometrium- like tissue outside of the uterus. secretory phospholipase a2 group iia (spla2-iia) and fatty acid binding protein4 (fabp4) play several important roles in the inflammatory diseases. objective: due to reported potential anti-inflammatory effects of ω-3 and ω-6 fatty acids, the pu...

bacterial utilize a multitude of methods to secretion of specific substrate across phospholipid membranes. these bacterial strategies can play many roles in promoting bacterial process, from enhancing pathogenesis to bacterial response to environmental condition. the secretion in bacterial species transfer and release performance substance such as proteins, enzymes and metabolites to environmen...

background: fasciola hepatica is one of the most important helminthes parasites and triclabendazole (tcbz) is routinely used for treatment of infected people and animals. secreted protease enzymes by the f. hepatica plays a critical role in the inva-sion, migration, nutrition and the survival of parasite and are key targets for novel drugs and vaccines. the aim of study was to determine the pro...

background: the aim of this study was to compare superoxide dismutase (sod) activity in fasciola hepatica and fasciola gigantica parasites. materials: f. gigantica and f. hepatica helminths were collected from abattoir and cultured in buffer media for 4 h at 37 °c. excretory-secretory (es) products were collected, centrifuged and stored at - 20 ◦ c. e-s protein concentration was measured by bra...

fasciolosis diagnosis, due to low sensitivity of coprological diagnostic method has been challenging for a long period. in this study, dot-elisa, one of the simplest and the most sensitive tests in this regard, was evaluated using excretory-secretory antigens of fasciola hepatica to diagnose human fasciolosis three groups consisting of patients infected with fasciolosis (n= 95), patients with o...

Background: Secretory proteins of IgE receptor activated mast cells and basophils play a pivotal role in the generation of immediate and long term immune responses in allergy and type I hypersensitivity. Objective: The present study aims to generate a 2-D map and profile of proteins secreted from a high secretory variant of the rat basophilic leukemia cell line, RBL-2H3.1, which in view of the ...

Background: Rat prostate gland which is used in various investigation has considerable morphological differences with other mammals. There are few reports about its structure. So, this study was carried on for determining of histomorphological structure of rat prostate. Materials and Methods: Five healthy adult male rats with average weight 20 ± 180 g and approximately 3 - 3.5 months age were s...

In the present study, pancreas glands in Mehraban breed of female sheep were histomorphometricallystudied in four different age groups included: fetus, newborn, sexually mature and old ages. The results ofhistomorphometrical analysis with regard to frequency and percentage of parenchymal and stromal structures such as, exocrine secretory units, secretory ducts, blood vessels, islets of Langerha...

background: inverse relationship between helminths infection and immune-mediated diseases has inspired researchers to investigate therapeutic potential of helminths in allergic asthma. helminth unique ability to induce immunoregulatory responses has already been documented in several experimental studies. this study was designed to investigate whether excretory/secretory (es) and somatic produc...