background: women with polycystic ovary syndrome have lower pregnancy rates, possibly due to the decreased uterine  receptivity.successful implantation depends on protein networks that are essential for cross-talk between the embryo and endometrium.apolipoprotein a1 has been proposed as a putative anti-implantation factor. in this study, we evaluated apolipoprotein a1 expression in human endome...

background: recent attention has focused on the expression of integrin molecules within the endometrium, and their relation to infertility. objective: the present prospective study was undertaken to determine whether the endometrium of women with unexplained infertility differs in the expression of very late activation antigens (vla) from the endometrium of normal fertile women. methods: thirty...

background: apelin is a mitogenic peptide; it has functions in vessel formation and cell proliferation. in this study we aimed to evaluate the serum and tissue levels and local expression pattern of apelin in eutopic and ectopic endometrium from patients with and without endometriosis and to compare the proliferative and secretory phase differences. methods: thirty women with endometriosis and ...

the purpose of this study was to investigate and compare whether the explant supernatants prepared from endometrial tissues during the proliferative phase, secretory phase and early pregnancy differ in immunosuppressive activity. specimens of nonpregnant endometrium from hysterectomies and normal first trimester decidua following elective aspiration termination of pregnancy were obtained. super...

Alteration in the release of female steroid hormones like progesterone and estrogen a systematic manner is due to periodic ovarian variation. The alteration causes physiological cardiovascular activities ultimately affects Electrocardiogram (ECG) parameters. : To analyze heart rate changes PR interval duration ST segment ECG during menstrual phases. investigate any change rate, different phases...

To investigate the possible role of the superoxide radical and its scavenging system in the human endometrium, the immunohistochemical distribution of superoxide dismutase (SOD), activities of SOD and lipid peroxide concentrations were studied in the human endometrium throughout the menstrual cycle and in early pregnancy. The endometrial epithelium showed a positive immunostaining for Cu, Zn-SO...

The purpose of this study was to investigate and compare whether the explant supernatants prepared from endometrial tissues during the proliferative phase, secretory phase and early pregnancy differ in immunosuppressive activity. Specimens of nonpregnant endometrium from hysterectomies and normal first trimester decidua following elective aspiration termination of pregnancy were obtained. ...

BACKGROUND The current understanding of hormonal regulation of matrix metalloproteinase-26 (MMP-26) in the primate endometrium is incomplete. The goal of this work was to clarify estrogen and progesterone regulation of MMP-26 in the endometrium of ovariectomized, hormone-treated rhesus macaques. METHODS Ovariectomized rhesus macaques (n= 66) were treated with estradiol (E(2)), E(2) plus proge...

It is widely assumed that, after ovulation, the human endometrium undergoes specific changes and becomes receptive to the implantation of embryo during the mid-secretory phase. When implantation does not take place, further changes occur which eventually result in the shedding of human endometrium. The present study was carried out to examine whether there are changes in the cytokine gene expre...