a 7-year-old castrated male german shepherd dog was presented with a 10-day history of intermittent lethargy, weakness and episodic seizures. laboratory findings after admission revealed hypoglycaemia and hyperinsulinaemia. provisional diagnosis of insulinoma was made based on the presence of concurrent hypoglycaemia and elevated insulin level. in exploratory laparotomy a small nodular mass was...

A 7-year-old castrated male German shepherd dog was presented with a 10-day history of intermittent lethargy, weakness and episodic seizures. Laboratory findings after admission revealed hypoglycaemia and hyperinsulinaemia. Provisional diagnosis of insulinoma was made based on the presence of concurrent hypoglycaemia and elevated insulin level. In exploratory laparotomy a small nodular mass was...

conclusions we described successful perioperative management of a child who underwent bilateral laparoscopic cortical sparing adrenalectomy and a repeated surgery for the residual tumor removal. case presentation the child might present with a spectrum of clinical manifestation including hypertension, headache, visual disturbances, and behavioral problems. a meticulous preoperative preparation ...

Familial GH-secreting tumors are seen in association with three separate hereditary clinical syndromes: multiple endocrine neoplasia type 1, Carney complex, and familial isolated pituitary adenomas.

Zollinger-Ellison syndrome results from a pancreatic tumor in the non-beta islet cells, which stimulates the maximal activity of the gastric acid-secreting cells, resulting in gastrointestinal ulceration of the mucosa. Multiple endocrine neoplasia type 1 (MEN 1) is a familial autosomal dominant syndrome that includes Zollinger-Ellison syndrome as part of it; however, Zollinger-Ellison syndrome ...

In a patient with multiple endocrine neoplasia type 2A (MEN2A), an inverted physiological ratio between urinary normetanephrines and metanephrines is an early marker of recurrence in epinephrine-secreting pheochromocytoma, and 131I MIBG treatment appears to be a useful therapeutic option in order to avoid multiple invasive surgical procedures in pheochromocytomatosis.

Veterinarians are often presented with complex adrenal neoplasia cases that have significant intraoperative challenges, which require the skills of an experienced surgeon. Perioperative evaluation and treatment of these patients can be equally challenging, and successful outcomes require a thorough understanding of the tumor types that affect the adrenal glands, as well as an understanding of a...

The objective of the study was to describe clinical, imaging, surgical and histological findings in a dog with Rathke's cleft cyst pituitary gland. A 6-year-old, female, neutered Staffordshire bull terrier presented an acute onset abnormal behaviour. Magnetic resonance imaging skull showed mass 12.9 mm (height) × 8.8 (width) 10.2 (length) height/brain area value 0.73 (reference <0.31). were sug...