Robust and accurate control of secondary cooling is vital to the successful operation of any caster and the production of high quality products. This is especially important in thin slab casters, because high casting speed and a tight machine radius often requires carefully-prescribed temperature profiles to avoid various cracking problems. This can be achieved only by successful control of the...

The solidification behavior and structure of continuous casting high rail U71Mn bloom, under different secondary cooling conditions and superheat, were numerically investigated using the Cellular Automaton-Finite Element (CAFE) model implemented with ProCAST software. Nail shooting and macro etch experiments of the bloom samples under different cooling conditions were conducted to verify the mo...

In this white paper, the warm water direct liquid cooling solution implementation in the CCS cluster solution is described. First, literature review of a range of direct liquid cooling solutions implemented in various competing vendors and their pros and cons are briefly presented. Design choices of datacenter cooling water distribution mechanisms (single loop vs primary/secondary loops), types...

We use the irradiated secondary star in the remnant of Nova Cyg 1975 as a probe of the cooling white dwarf. At superior conjunction the flux in the B band is dominated by the irradiated face of the secondary star. The heated face produces an orbital modulation which is dependent on the strength of the irradiating source. We demonstrate that the cooling rate of the white dwarf is consistent with...

OBJECTIVE Therapeutic hypothermia is a promising treatment to prevent secondary neurologic injury. Clinical utility is limited by systemic complications of global hypothermia. Selective brain cooling remains a largely uninvestigated application. We review techniques of inducing selective brain cooling. METHOD Literature review. RESULTS Strategies of inducing selective brain cooling were div...

The detailed mathematical model of heat and mass transfer of steel ingot of curvilinear continuous casting machine is proposed. The process of heat and mass transfer is described by nonlinear partial differential equations of parabolic type. Position of phase boundary is determined by Stefan conditions. The temperature of cooling water in mould channel is described by a special balance equation...

Microscale freeze-drying makes rapid process cycles possible for early-stage formulation development. To investigate the effects of equipment scale and cooling rate on the solid state properties and the protein's secondary structure of a sample, three binary formulations of catalase were prepared and freeze-dried with sucrose, mannitol, or (2-hydroxypropyl)-β-cyclodextrin (HP-β-CD). The protein...

BACKGROUND There are currently no promising therapies available to treat or prevent peripheral neuropathy (PN) induced by anticancer drugs in a cumulative dose-dependent manner. In this study, we investigated the efficacy of regional cooling of hands and feet in preventing paclitaxel (PTX)-induced PN. METHODS Patients with gynecologic cancer who received a tri-weekly cycle of chemotherapy inc...