In elderly populations, frailty is associated with higher mortality risk. Although many frailty scores (FS) have been proposed, no single score is considered the gold standard. We aimed to evaluate the agreement between a wide range of FS in the English Longitudinal Study of Ageing (ELSA). Through a literature search, we identified 35 FS that could be calculated in ELSA wave 2 (2004-2005). We e...

OBJECTIVE To evaluate a healthy lifestyle intervention to reduce adiposity in children aged 5 to 9 years and assess whether adding parenting skills training would enhance this effect. PARTICIPANTS AND METHODS We conducted a single-blinded randomized controlled trial of prepubertal moderately obese (International Obesity Task Force cut points) children, aged 5 to 9 years. The 6-month program t...

BACKGROUND AND OBJECTIVE There is ongoing concern that stimulant medications may adversely affect growth. In a sample of attention-deficit/hyperactivity disorder (ADHD) cases and controls from a population-based birth cohort, we assessed growth and the association between stimulant treatment and growth. METHODS Subjects included childhood ADHD cases (N = 340) and controls (N = 680) from a 197...

The association between isolated systolic hypertension (ISH) and incident heart failure (HF) has not been prospectively studied in a propensity-matched population of ambulatory older adults. Of the 5795 participants in the public-use copy of the Cardiovascular Health Study data set, 5248 had diastolic blood pressure <90 mm Hg and were free of HF at baseline. Of these, 2000 (38%) had ISH, define...

background: dual-energy x-ray absorptiometry (dxa) is considered the gold standard for non-invasive measurement of bone mass. t-scores and z-scores are used to present the results of bone mass. the present study was designed to evaluate the discordance between t-scores and z-scores calculated at a same level and its relation with age, gender and body mass index (bmi) in a representative sample ...

A retrospective longitudinal study was performed to quantify foetal growth velocities in twin pregnancies and to determine the effect of variables specific to twin pregnancies on growth velocity. Foetal growth velocity standard deviation (Z) scores were calculated from serial ultrasound data using published singleton reference data for 131 consecutive sets of twins from 30 to 37 weeks' gestatio...

OBJECTIVES To examine the association of orthostatic hypotension with incident heart failure (HF) in older adults. METHODS Of the 5,273 community-dwelling adults aged 65 years and older free of baseline prevalent HF in the Cardiovascular Health Study, 937 (18%) had orthostatic hypotension, defined as ≥20 mmHg drop in systolic or ≥10 mmHg drop in diastolic blood pressure from supine to standin...

A k-hypertournament is a complete k-hypergraph with each k-edge endowed with an orientation, that is, a linear arrangement of the vertices contained in the edge. In a k-hypertournament, the score si (losing score ri) of a vertex vi is the number of arcs containing vi in which vi is not the last element (in which vi is the last element). The total score of vi is defined as ti = si − ri. In this ...