Introduction: Due to interesting therapeutic properties of 46Sc and antineoblastic antibiotic, bleomycin (BLM), 46Sc-bleomycin (46Sc-BLM) was developed as a possible therapeutic compound. Methods: In this work, Sc-46 chloride was obtained by thermal neutron flux (4 × 1013 n.cm-2.s-1) of natural metallic scandium sample followed ...

In this paper we address some of the concerns raised by Butterworth and Punt (1994) in SC/46/AS2 regarding the Bayesian synthesis method. We argue that the sensitivity of the Bayesian synthesis approach is similar to that of alternative methods, and that the ease with which sensitivity can be detected is one of the advantages of the method. We also note that some of the examples in SC/46/AS2 us...

This experiment tested the role of oropharyngeal and gastric afferents on hypothalamic activation in dehydrated rats instrumented with gastric fistulae and allowed to drink water or isotonic saline compared with euhydrated controls (CON). Rats were water deprived for 48h (48 WD) or 46h WD with 2h rehydration with water (46+W) or isotonic saline (46+S). 46+W and 46+S rats were given water with f...

UNLABELLED In recent years, (47)Sc has attracted attention because of its favorable decay characteristics (half-life, 3.35 d; average energy, 162 keV; Eγ, 159 keV) for therapeutic application and for SPECT imaging. The aim of the present study was to investigate the suitability of (47)Sc for radionuclide therapy in a preclinical setting. For this purpose a novel DOTA-folate conjugate (cm10) wit...

New data for the $^\mbox{nat}$V(p,x) reactions have been measured in range 26-70 MeV, with production of nuclides $^{47}$Sc, $^{43}$Sc, $^{44m}$Sc, $^{44g}$Sc, $^{46}$Sc, $^{48}$Sc, $^{42}$K, $^{43}$K, $^{48}$V, $^{48}$Cr, $^{49}$Cr, and $^{51}$Cr. The focus is on a $\beta^-$-emitter suitable innovative radiotheranostic applications nuclear medicine. cross sections this radionuclide its contami...

New data for the $^\mbox{nat}$V(p,x) reactions have been measured in range 26-70 MeV, with production of nuclides $^{47}$Sc, $^{43}$Sc, $^{44m}$Sc, $^{44g}$Sc, $^{46}$Sc, $^{48}$Sc, $^{42}$K, $^{43}$K, $^{48}$V, $^{48}$Cr, $^{49}$Cr, and $^{51}$Cr. The focus is on a $\beta^-$-emitter suitable innovative radiotheranostic applications nuclear medicine. cross sections this radionuclide its contami...

Sodium chlorite (SC) was shown to have strong efficacy both as a sanitizer to reduce microbial growth on produce and as a browning inhibitor on fresh-cut apples in previous experiments. This study was undertaken to investigate the inhibitory effect of SC on polyphenol oxidase (PPO) and the associated mechanisms. The experiment showed that SC had a strong inhibition of apple PPO. The extent of i...

BACKGROUND Gallbladder cancers (GBCs) are highly aggressive cancers with high mortality. However, biological markers for the progression and prognosis of GBC are currently unavailable in the clinic. OBJECTIVE To identify biomarkers for predicting GBC metastasis and prognosis. METHODS We examined ALDH1A3 and GPX3 expressions in 46 squamous cell/adenosquamous carcinomas (SC/ASC) and 80 adenoc...