introduction: periodontitis is a multi-factorial inflammatory disease of periodontium. a precise mechanism in which smoking affects periodontium is not accurately understood. this study was planned to survey salivary osteocalcin (oc) level among smokers with chronic periodontitis and its comparison to non-smoker patients which may help achieve a better understanding of mechanisms being involved...

OBJECTIVES To assess the effect of topical application of melatonin to the gingiva on salivary fluid concentrations of acid phosphatase, alkaline phosphatase, osteopontin, and osteocalcin. STUDY DESIGN Cross-sectional study of 30 patients with diabetes and periodontal disease and 30 healthy subjects. Diabetic patients were treated with topical application of melatonin (1% orabase cream formul...

In astronauts and cosmonauts, exposure to microgravity has been associated with several physiological changes, including an osteoporosis like loss of bone mass. It has been reported that head-down tilt bed-rest studies mimic many of the observations seen in space flights. There has been no study of the effects of mandibular bone and alveolar bone loss in both sexes under conditions of simulated...

Background: Lead (Pb) is a heavy metal that has devastating effects on many animal tissues. In this study we investigated the effects of orally-dosed lead acetate II on osteocalcin gene (osteocalcin) expression in mesenchymal stem cells grown in an osteogenic medium. Osteocalcin is an abundant bone matrix differentiation protein. Methods: Twelve male Wistar rats were divided into three groups ...

Introduction: Experimental evidence suggests positive effects of physical activity on skeletal mass. Biochemical markers determine the response rate of bone metabolism to physical activity. Therefore, the aim of this study was to investigate the effect of Pilates exercise training on serum osteocalcin and parathormone levels in inactive and overweight women. Methods: 28 healthy overweight wome...

To study the correlations between serum osteocalcin and glucose metabolism in patients with type 2 diabetes, 66 cases were collected to determine total osteocalcin, undercarboxylated osteocalcin, fasting blood glucose, fasting insulin, and HbA1c. Osteocalcin concentrations were compared between groups of different levels of HbA1c, and parameters of glucose metabolism were compared between group...