cigarette smoke is injurious to both oral cavity and internal body environment. saliva is the firstbody fluid to encounter the dangerous smoke. the aim of our present study was, therefore, toevaluate the influence of smoking on the antioxidant activity of saliva of healthy smokers.antioxidant capacity of saliva was determined using different methods in the centrifuged saliva from25 male smokers...

the first reaction between food components and biological tissues occurs in the oral cavity. saliva modulates the ecosystem in the oral cavity and plays a critical role in oral homeostasis. in addition, saliva is a first line of defense against free radical-mediated stress. salivary antioxidant defense mechanisms seem to be very important. in this study we discuss in detail free radicals (fr) a...

in our previous studies we have evaluated the role of antioxidants and trace elements in potentially malignant disorders and cancers of the oral cavity, taking into consideration the importance of antioxidants as biomarkers in cancer detection. we felt that other than evaluation, the correlation and interdependence that existed among antioxidants and trace elements require further evaluation in...

Changes in Salivary Antioxidants Patients with Oral Squamous Cell Carcinoma: Systematic Review Study and Meta-Analysis

OBJECTIVE In our previous studies we have evaluated the role of antioxidants and trace elements in potentially malignant disorders and cancers of the oral cavity, taking into consideration the importance of antioxidants as biomarkers in cancer detection. We felt that other than evaluation, the correlation and interdependence that existed among antioxidants and trace elements require further eva...

Significant increase in the salivary gland weight was observed after exposure to single therapeutic dose of 3.7 MBq of 131I in mice. Pre-supplementation of antioxidants, O. sanctum leaf extract, turmeric extract and vitamin E for 15 days before 131I exposure demonstrated significant reduction in the salivary gland weight. No major histopathological changes were observed in the salivary gland of...

INTRODUCTION Oxidative stress and antioxidants play an important role in the pathogenesis of inflammatory disease, including chronic periodontitis (CP). Saliva contains enzymatic (glutathione peroxidase - GPx, superoxide dismutase - SOD, etc.) and non-enzymatic (albumin - ALB, uric acid - UA, glutathione, etc.) antioxidants. OBJECTIVE The aims of this study were to investigate: a) level of SO...

Oxidative stress plays a crucial role in dementia pathogenesis; however, its impact on salivary secretion and salivary qualities is still unknown. This study included 80 patients with moderate dementia and 80 healthy age- and sex-matched individuals. Salivary flow, antioxidants (salivary peroxidase, catalase, superoxide dismutase, uric acid and total antioxidant capacity), and oxidative damage ...

Background: The cigarette compounds are associated with the increase in the incidence of oral cancer andprecancerous lesions. Salivary antioxidant system plays an important role in anti-carcinogenic capacity ofsaliva. Cotinine, a nicotine metabolite, has a longer half-life in comparison with nicotine and is a suitablemarker for exposure to cigarette smoke. This study aims to measure total antio...