The properties relevant to pharmacokinetics and pharmacodynamics of four series of synthesized s-triazine derivatives have been studied by Quantitative structure-retention relationship (QSRR) approach. The chromatographic behavior of these compounds was investigated by using reversed-phase high performance thin-layer chromatography (RP-HPTLC). Chromatographic retention (RM0) was correlated with...

the properties relevant to pharmacokinetics and pharmacodynamics of four series of synthesized s-triazine derivatives have been studied by quantitative structure-retention relationship (qsrr) approach. the chromatographic behavior of these compounds was investigated by using reversed-phase high performance thin-layer chromatography (rp-hptlc). chromatographic retention (rm0) was correlated with...

The properties relevant to pharmacokinetics and pharmacodynamics of four series of synthesized s-triazine derivatives have been studied by Quantitative structure-retention relationship (QSRR) approach. The chromatographic behavior of these compounds was investigated by using reversed-phase high performance thin-layer chromatography (RP-HPTLC). Chromatographic retention (RM0) was correlated with...

The properties relevant to pharmacokinetics and pharmacodynamics of four series of synthesized s-triazine derivatives have been studied by Quantitative structure-retention relationship (QSRR) approach. The chromatographic behavior of these compounds was investigated by using reversed-phase high performance thin-layer chromatography (RP-HPTLC). Chromatographic retention (R M (0)) was correlated ...

The metabolism of 2-chloro-4-ethylamino-6-isopropylamino-s-triazine (atrazine) in the resistant species, corn (Zea mays L.) and sorghum (Sorghum vulgare Pers.) was not the same. In corn, atrazine was metabolized via both the 2-hydroxylation and N-dealkylation pathways while sorghum metabolized atrazine via the N-dealkylation pathway. Atrazine metabolism in corn yielded the metabolites, 2-hydrox...

Within a study of the temperature dependence of NQR frequencies in some s-triazine derivatives [1], resonance frequencies at 4.2 K were determined in melamine, cyanuric acid, and cyanuric chloride. New lines, which were not reported so far, were detected in two of these compounds. In melamine, nine more lines were found as already described in [4], In cyanuric chloride, two more lines were foun...

A liquid chromatography method has been developed and validated for the determination of mathematical models for prediction of the lipophilicity of s-triazine compounds. Correlation between retention factors, RM 0 , of several s-triazine derivatives and their physico-chemical and structural properties has been studied by TLC on silica gel impregnated with paraffin oil. The research in this pape...

Two monopodal (2,4-dichloro-6-(3-hydroxytyramine)-1,3,5-triazine) and tripodal (2,4,6-(3-hydroxytyramine)-1,3,5-triazine) s-triazine derivatives were prepared through the reaction of cyanuric chloride (2,4,6-trichloro-1,3,5-triazine) and 3-hydroxytyramine hydrochloride (dopamine hydrochloride). The structures of the compounds were identified by FT-IR, 1H NMR, 13C NMR, thermal analysis and eleme...