The essential oil from the aerial parts of Salvia sclarea L., growing wild in Tajikistan, were obtained by hydrodistillation and analyzed by gas chromatography – mass spectrometry. A total of 59 compounds were identified representing 94.2% of total oil composition. Major components of the essential oil were linalyl acetate (39.2%), linalool (12.5%), germacrene D (11.4%), α-terpineol (5.5%), ger...

The essential oil (EO) from Salvia sclarea was shown to increase the susceptibility of methicillin resistant Staphylococcus epidermidis (MRSE) isolates to oxacillin. The purpose of this study was to investigate the effect of EO from S. sclarea on expression of mecA gene of MRSE carrying different types of staphylococcal chromosomal cassette (SCCmec) and to evaluate potential synergistic effect ...

The essential oils obtained by hydrodistillation of dried aerial parts of Salvia sclarea L. plants, regenerated in vitro and reproduced from seeds, were analyzed by GC and GC-MS. The oils from in vitro and in vivo plants were compared in respect to their chemical composition as well as antimicrobial and cytotoxic activities. The chemical profiles of both oils were very similar, although the yie...

Four diterpenoids, ferruginol, salvipisone, aethiopinone and 1-oxoaethiopinone, were isolated from transformed roots of Salvia sclarea. Salvipisone and aethiopinone showed relatively high cytotoxicity against HL-60 and NALM-6 leukemia cells (IC50 range 0.6-7.7 microg/ mL which is equal to 2.0-24.7 microM), whereas 1-oxoaethiopinone and ferruginol were less active in this regard. Moreover, we ha...

background: the seeds of some medicinal plants and their compounds have long been valued for their numerous health benefits. objective:to investigate some physical and chemical properties of salvia spp. methods: some physico-chemical properties in five species of salvia seeds (consisted of s. officinalis l., s. macrosiphon l., s. hypoleuca l., s. sclarea l. and s. nemorosa l.) were measured at ...

Background: The seeds of some medicinal plants and their compounds have long been valued for their numerous health benefits. Objective:To investigate some physical and chemical properties of Salvia spp. Methods: Some physico-chemical properties in five species of Salvia seeds (consisted of S. officinalis L., S. macrosiphon L., S. hypoleuca L., S. sclarea L. and S. nemorosa L.) were measured ...

The plants of the genus Salvia synthesize several types of secondary metabolites with antimicrobial, cytotoxic, and radical scavenging activities and are used in the folk medicine of different countries. Eleven Salvia species including S. aegyptiaca, S. aethiopis, S. atropatana, S. eremophila, S. hypoleuca, S. limbata, S. nemorosa, S. santolinifolia, S. sclarea, S. syriaca, and S. xanthocheila ...