BACKGROUND The cultivation of saffron is expanding through the southeast of Iran, and allergy to saffron pollen occurs in workers involved in processing this plant. We aimed to clone, sequence and express a major allergen involved in saffron pollen allergy, and to compare the recombinant with the natural allergen. METHODS The N-terminal amino acid sequence of Cro s 1, an allergen from saffron...

BACKGROUND Lipid transfer proteins (LTPs) are relevant allergens, and have recently been proposed as model plant allergens from fruit, vegetables, seeds, and pollens. However, no LTP spice allergen has been characterized to date. OBJECTIVES To identify and isolate saffron LTPs and to explore their relevance in saffron allergy. METHODS Six patients with rhinitis and positive skin prick test ...

From ancient times, saffron dried stigmas of Crocus sativus L. is widely used as a drug against different human diseases. In the beginning of 1990 ́s scientific literature reported for the first time the antitumor activity of saffron. During the last decade different laboratories of the world (including ours) have accumulated sufficient scientific evidence to suggest that saffron, and its main i...

The separation possibility of stigma from the other parts of saffron flower using its aerodynamic properties was investigated and a vertical air column was designed on the basis of the obtained results. Terminal velocities of three parts of saffron flower, including petal, stigma and anther within four days after harvest were studied. Significant difference between terminal velocity of stigma (...

Cerebral ischemia produces brain damage and related behavioral deficits such as memory. In this study, a rat model of chronic cerebral hypoperfusion was used to determine whether saffron extract and crocin, which are potent antioxidants and free radical scavengers, can reduce vascular cognitive impairment. Male adult Wistar rats were administered different doses of an aqueous solution of crocin...

background: the cultivation of saffron is expanding through the southeast of iran, and allergy to saffron pollen occurs in workers involved in processing this plant. we aimed to clone, sequence and express a major allergen involved in saffron pollen allergy, and to compare the recombinant with the natural allergen. methods: the n-terminal amino acid sequence of cro s 1, an allergen from saffron...

Background: The cultivation of saffron is expanding through the southeast of Iran, and allergy to saffron pollen occurs in workers involved in processing this plant. We aimed to clone, sequence and express a major allergen involved in saffron pollen allergy, and to compare the recombinant with the natural allergen. Methods: The N-terminal amino acid sequence of Cro s 1, an allergen from saff...

Saffron is a spice obtained from the dried stigmas of the purple-flowered saffron crocus (Crocus sativus L.). The determination of the water content in saffron is very important in order to establish its microbiological stability and consequently to determine the commercial value. The average moisture content in dried saffron powder ranges between 10-12% causing a slow degradation of the produc...

BACKGROUND Allergy to Saffron (Crocus sativus) pollen has been described in people involved in processing of saffron flower stamens. Profilins have been identified as a pan-allergen in different plant pollens and foods. This molecule is an actin-binding protein with a molecular weight of 12-16 kDa found in eukaryotic species. OBJECTIVE The aim of this study was to generate monoclonal antibody...

The objective of this study was to investigate the effects of saffron as a natural sunscreen and moisturizer. The pollens of the saffron were dried and powdered in a grinder. The experimental formulations included a homosalate (8%) lotion reference, lotions with 2, 4 and 8% of grinded saffron, and the control lotion base without saffron. The lotions containing saffron were prepared like homosal...