introduction: inflammation and edema symptoms are physiological response to triggers that can be induced by different mediators such as cytokines. rheumatoid arthritis is the most common form of arthritis which is characterized by chronic inflammation of the synovial membrane, severe and debilitating pain and progressive cartilage injury. it is clear that cytokines are involved in different sta...

PURPOSE Although several clinical trials have proven the efficacy of adjuvant S-1 treatment in gastric cancers, it is still unclear which patients receive the most benefit. In this study, we prospectively recruited patients with locally advanced gastric cancer who had undergone curative resection followed by adjuvant S-1 administration to investigate which factors affect the outcomes. MATERIA...

aviecennia marina (avicenniaceae) is an endemic plant that widely distributed in the southern parts of iran. this plant has been used as treatment of rheumatism arthritis among the inhabitants of southern parts of iran. the avicennia marina hydroalcoholic extract was prepared and its protective efficacy was investigated using measurement of ankle diameter, total wbc and rbc count, esr, and pro-...

results cloning and subcloning of the flic gene were confirmed by colony pcr, restriction enzymes digestion and dna sequencing of the recombinant plasmids pprime-flic and pvax-flic. the expression of flagellin protein in eukaryotic cells was approved by immunofluorescence assay (ifa), western blotting analysis and the reverse transcriptase polymerase chain reaction (rt-pcr) method. conclusions t...

experiments wee performed to evaluate the contralateral effect of adjuvant induced mono arthritis. in these experiments laser doppler imaging (ldi) was used to investigate changes in blood flow. adjuvant was applied to induce chronic inflammation. temperature and knee diameter increased in the first week after administration in the administrated knee joint.substance p (sp) (a neruokinin with a ...

S-1 has been recommended as adjuvant chemotherapy in patients after curative surgery for gastric cancer. However, some patients suffer recurrence even after S-1 adjuvant chemotherapy. The present study was conducted to find a predictive marker of the efficacy of S-1 adjuvant chemotherapy. We examined the microRNA (miRNA) expression of 35 patients who underwent S-1 adjuvant chemotherapy after cu...

OBJECTIVE To report the management of a rare case of ovarian hyperstimulation syndrome (OHSS) induced by tamoxifen therapy for breast cancer in a 50-year-old woman. DESIGN Case report. SETTING Gynecology outpatient department of a university hospital. PATIENT(S) A 50-year-old premenopausal patient with a history of breast cancer was prescribed adjuvant treatment with tamoxifen. INTERVEN...

background outer membrane protein d (pd) is a highly conserved and stable protein in the outer membrane of both encapsulated (typeable) and non-capsulated (non-typeable) strains of haemophilus influenzae. as an immunogen, pd is a potential candidate vaccine against non-typeable h. influenzae (nthi) strains. objectives the aim of this study was to determine the cytokine pattern and the opsonic a...