Objective(s): Resveratrol (RSV) is a naturally occurring plant polyphenol with cardioprotective, neuroprotective, immunoregulatory, and anticancer properties and is biologically effective against various diseases. This study aimed to investigate the chemopreventive effect of different doses of RSV against hepatocellular carcinoma (HCC) induced by  diethylnitrosamine (D...

conclusions this study delineated the beneficial role of rsv for growth regulation of skin cancer cells and highlighted the involvement of rsv in the induction of apoptosis in a431 cells. these findings might conduct evidence into the oncolytic properties of rsv in the skin cancer. further studies are required to indicate intracellular targets for rsv-induced apoptosis in skin cancer cells. res...

Background: Resveratrol (RSV) provides several important biological functions in wide variety of cells. In this study, we investigated the molecular mechanisms underlying anti-inflammatory effect of RSV on HepG2 cells by assessing the gene expression of RelA and c-Jun- subunits of NF-κB and AP-1 transcription factors.    Methods: HepG2 cells were settled in a serum- free medium...

MicroRNAs has been shown to regulate lipogenesis in liver. The aim of the present study was to investigate whether the effects of resveratrol (RSV) on lipogenesis is associated with the changes in the expression of two miRNAs (miR-107 and miR-10b) that regulate lipogenic pathways. 30 wild type C57BL/6j male mice were randomly fed three diets: a standard chow diet (ND), a high fat diet (HFD, 60%...

To evaluate the effects of multi-walled carbon nanotubes (MWCNT) on a host immune system, we assayed them using murine model respiratory syncytial virus (RSV) infection. MWCNT suspended in solution were intranasally administered to mice days 1, 3, and 5 before RSV On day post-infection, levels representative inflammatory markers (interferon-γ, chemokines CCL3 CCL5) bronchoalveolar lavage fluid ...

MicroRNAs has been shown to regulate lipogenesis in liver. The aim of the present study was to investigate whether the effects of resveratrol (RSV) on lipogenesis is associated with the changes in the expression of two miRNAs (miR-107 and miR-10b) that regulate lipogenic pathways. 30 wild type C57BL/6j male mice were randomly fed three diets: a standard chow diet (ND), a high fat diet (HFD, 60%...

Objective(s): Both caloric restriction (CR) and resveratrol (RSV) have been shown to improve learning and memory, but their potential effects in juvenile animals were unknown. Here, we evaluated the effects of RSV and CR on learning and memory function in juvenile mice and investigated potential molecular mechanisms. Methods: Six-week-old C57BL/6J mice were assigned to one of three different d...

Background: Respiratory Syncytical virus infection is the most common cause of bronchiolitis and viral pneumonia in infancy. Objective: To investigate the placental transfer of RSV-specific IgG in Iranian mothers. Methods: The antibodies were measured in sera of 146 mother/newborn pairs using a commercially available indirect Enzyme Linked Immunosorbent Assay (ELISA). The studied subjects were ...

nasopharyngeal swab samples from patients with an acute flu-like illness were evaluated for the presence of respiratory syncytial virus (rsv) from october 1996 to march 1998. the relative frequency and seasonal distribution of rsv was assessed. in addition, the virus correlated with specific clinical signs and symptoms. during the study, 268 samples were collected from children under the age of...

background respiratory syncytial virus (rsv) can cause acute respiratory infection (ari) in infants and young children. objectives this study was conducted to determine the incidence of rsv infection and its subgroups among children with ari. materials and methods a total of 100 throat samples were collected from hospitalized children with ari in different hospitals across the khuzestan provinc...