Background & Aims: Tyrosinase is the most important enzyme in the production of pigments of the skin, eyes, and hair follicles. The enzyme is encoded by tyrosinase gene (TYR) or oculocutaneous albinism type 1A (OCA1A). Mutations in TYR gene result in pigmentation disorders such as albinism in humans. In view of the large number of mutations reported in this gene, the aim of this study was to id...

small supernumerary marker chromosomes (ssmc) are still a major problem in clinical cytogenetics as they cannot be identified or characterized unambiguously by conventional cytogenetics alone. on the other hand, and perhaps more importantly in prenatal settings, there is a challenging situation for counseling how to predict the risk for an abnormal phenotype, especially in cases with a de novo ...

background spirulina is one of the most profitable known microalgae in the world, which is used as food and superfood. in the other hand, spirulina is a useful source of healthy components. it seems that the spirulina is transformable so that the introduction of a selectable marker is needed. objectives the purpose of this study was to determine a suitable selection marker for spirulina platens...

Tumour markers are substances that are produced either by the tumour itself or by the body in response to the presence of cancer or certain benign conditions that can aid in the diagnosis of cancer. The subject of tumour markers is a broad one, and there is an abundance of data. A literature review of potential molecular markers relevant to oral neoplasia was undertaken in terms of a perspectiv...

background: inhibin is a dimeric glycoprotein that has a depressive effect on the anterior hypophyse secretion. the level of this tumor marker is undetectable in menopause women. in patients with gynecological cancer, especially granulosa and epidermal-type (mucinous), ovarian cancers considerable increase in the serum level of inhibin has been reported. the increased level of inhibin has been ...

a greenhouse experiment was conducted in 2013 in research lab of karaj islamic azad university to determine the yield and activity of chemical markers as the response to different concentrations of cadmium (cd) (0, 5, 10 and 20 mg of cd/kg of soil) in wheat cultivars (karaj 1 and karaj 2). treatments were tested in a factorial experiment with four replications in 7.5 kg plastic pots. the respon...

objective: to evaluate whether systemic inflammatory markers (neutrophil to lymphocyte ratio (nlr), platelet to lymphocyte ratio (plr) and red blood cell distribution width (rdw) to platelet ratio (rpr)) can be used as reliable markers for the diagnosis of premature ovarian insufficiency (poi) and to determine if there is a relationship between these markers and follicle stimulating hormone (fs...

background: the availability of testis specific genes will be of help in choosing the most promising biomarkers for the detection of testicular sperm retrieval in patients with non-obstructive azoospermia (noa). testis specific chromodomain protein y 1 (cdy1) is a histone acetyltransferase which concentrates in the round spermatid nucleus, where histone hyperacetylation occurs and causes the re...