We argue that achieving very high data rates can be accomplished by moving away from system-centric radio resource management (RRM), used in the cellular radio access network (RAN) architecture, and toward advanced user-centric RRM, obtained with top-down RAN protocol design. Systemcentric RRM uses a divide-and-conquer approach, which assigns resources to cells first and to users second. On the...

Telomerase-reverse transcriptase (TERT) plays an essential catalytic role in maintaining telomeres. However, in animal systems telomerase plays additional non-telomeric functional roles. We previously screened an Arabidopsis cDNA library for proteins that interact with the C-terminal extension (CTE) TERT domain and identified a nuclear-localized protein that contains an RNA recognition motif (R...

The Quasi-Reversibility Regularization Method (Q-RRM) provides stable approximate solution of the Cauchy problem Helmholtz equation in Hilbert space by providing either additional information Laplace-type operator or imposed boundary conditions on equation. To help bridge this gap literature, a Modified Quasi-reversibility (MQ-RRM) is introduced to provide both occurring and equation, resulting...

OBJECTIVE Contemporary approaches to medical decision-making advise that clinicians should respect patients' decisions. However, patients' decisions are often shaped by heuristics, such as being guided by emotion, rather than by objective risk and benefit. Risk-reducing mastectomy (RRM) decisions focus this dilemma sharply. RRM reduces breast cancer (BC) risk, but is invasive and can have iatro...

DEAD-box proteins share a structurally similar core of two RecA-like domains (RecA_N and RecA_C) that contain the conserved motifs for ATP-dependent RNA unwinding. In many DEAD-box proteins the helicase core is flanked by ancillary domains. To understand the regulation of the DEAD-box helicase YxiN by its C-terminal RNA recognition motif (RRM), we investigated the effect of RNA binding to the R...

High-speed railway (HSR) communications will become a key feature supported by intelligent transportation communication systems. The increasing demand for HSR communications leads to significant attention on the study of radio resource management (RRM), which enables efficient resource utilization and improved system performance. RRM design is a challenging problem due to heterogenous quality o...

A phased array radar has the ability to rapidly and adaptively position beams and adjust dwell times, thus enabling a single radar to perform multiple functions, such as surveillance, tracking and fire control. A radar resource manager prioritises and schedules tasks from the various functions to best use available resources. Networked phased array radars that are connected by a communication c...

Serine/arginine (SR) proteins, one of the major families of alternative-splicing regulators in Eukarya, have two types of RNA-recognition motifs (RRMs): a canonical RRM and a pseudo-RRM. Although pseudo-RRMs are crucial for activity of SR proteins, their mode of action was unknown. By solving the structure of the human SRSF1 pseudo-RRM bound to RNA, we discovered a very unusual and sequence-spe...

The Information Spectrum Method (ISM) and the Resonant Recognition Model (RRM) represent a methodology based on signal processing that analyses characteristic spectral motifs in DNA/RNA and protein sequences. Some inconsistencies have been reported recently with regard to the spectral characterization of speciÞc biological sequences utilizing the ISM (RRM) and this motivated examination of the ...