Background and Aims: One of the major causes of acute diarrhea in children during the cold season in Iran is infection by rotavirus. Children infected with rotavirus often require hospitalization. Several studies on human and animals have shown that enterotoxigenic Escherichia.coli and rotavirus are the most common coinfection causing diarrhea. There are other reports indicating occurrence of r...

rotavirus is the most important pathogen responsible for acute diarrhea in infants and young children. the incidence of rotavirus infection was studied in 156 children less than six years of age who were suffering from acute gastroenteritis, between february 22, 2006 and february 21, 2007 in mashhad. rotavirus antigen was detected by latex agglutination test (rotascreen) in 28.8% of the stool s...

conclusions this report aimed to increase awareness of the occurrence of extra-intestinal systemic manifestations of rotavirus infection. although such cases may be rare, they still suggest that that rotavirus is a systemic viral infection. case presentations we report three pediatric cases of rotavirus infection: one accompanied by encephalopathy and two with elevated hepatic transaminase acti...

background and aims: one of the major causes of acute diarrhea in children during the cold season in iran is infection by rotavirus. children infected with rotavirus often require hospitalization. several studies on human and animals have shown that enterotoxigenic escherichia.coli and rotavirus are the most common coinfection causing diarrhea. there are other reports indicating occurrence of r...

Background and Aims: Rotaviruses are one of the main causative agents of acute viral gastroenteritis in both young human and animals. Several methods have been used for diagnosis of rotavirus infection. Most of these methods are not easily available in Iran. Methods: In our study attempt was made to develop a method which could replace the commercially imported Kit. Rota virus was purified and...

background: the recent studies show that rotavirus is important cause of the acute gastroenteritis. the aim of this review is to estimate the number of rotavirus infection among iranian children by performing a systematic review and estimating a pooled data. methods: we performed a systematic literature review in relevant databases including pubmed, medline, ovid, sid, magiran, and iranmedex. s...

That rotavirus infection can cause neurological symptoms in young children has been well established. However, it is surprising why rotavirus infection has been overlooked as a cause of neonatal seizures for many years, despite significant research interest in neonatal rotavirus infection. Neonates are the age group most vulnerable to seizures, which are typically attributed to a wide range of ...

Rotavirus is the most important worldwide cause of severe gastroenteritis in infants and young children. Intestinal epithelial cells are the principal targets of rotavirus infection, but the response of enterocytes to rotavirus infection is largely unknown. We determined that rotavirus infection of HT-29 intestinal epithelial cells results in prompt activation of NF-kappaB (<2 h), STAT1, and IS...

Background & Aims: Diarrheal diseases are one of the major causes of morbidity and mortality in infants and toddlers in developing countries and Rotavirus is the single most important cause of severe infantile gastroenteritis worldwide. This study was conducted to estimate the frequency and clinical manifestations of rotavirus infection in children below 3 years old with acute gastroenteritis r...