Group A rotaviruses were first detected in pigs suffering from diarrhea in 1975. It is generally accepted that multiple rotavirus strains are present in most if not all conventional swine herds. Rotavirus infections are very prevalent and are commonly associated with diarrhea in suckling and weaned pigs. Early studies also demonstrated that porcine rotaviruses are physically and serologically s...

Piglets weaned abruptly and precociously at 3 weeks of age and placed in a crowded nursery commenced diarrhea 3 to 5 days later. Death losses were low (approximately 6%), but weight gain ceased for 2 weeks. Large numbers of rotavirus (reo-like) particles were seen by electron microscopy in diarrhetic fluids. Sections of intestines showed a loss of adsorptive surface in that villi were shortened...

Introduction: In developing countries, rotaviral diarrhea is the cause of death of many children, and is the main etiology of gastroenteritis in children under 2 years old. Determination of the prevalence of rotaviral infection can reveal the impact of this infection in this group of the population and provides clues as to the strategies for prevention and treatment protocols for children s...

A rapid and simple technique for diagnosis of rotaviral diarrhea is polyacrylamide gel electrophoresis (PAGE) of dsRNA extracted from fecal samples. To determine the electrophoretype of Iranian calf rotavirus, 23 rotaviral positive fecal samples from diarrheic Holstein calves at the age of less than one month in Tehran region were examined. The viral dsRNA was extracted with phenol-chloroform, ...

Rotaviral infection in neonatal animals and young children leads to acute self-limiting diarrhea, but infected adults are mainly asymptomatic. Recently, significant in-roads have been made into our understanding of this disease: both viral infection and virally manufactured nonstructural protein (NSP)4 evoke intracellular Ca(2+) ([Ca(2+)]i) mobilization in native and transformed gastrointestina...

BACKGROUND This review was designed to assess the evidence from randomized controlled trials on effects of probiotics in the treatment and prevention of acute infectious diarrhea in infants and children. METHODS A systematic review of published, randomized, double-blind, placebo-controlled trials on probiotics in the treatment or prevention of acute diarrhea defined as >3 loose or watery stoo...

Since the turn of the century, Escherichia coli has been implicated in the etiology of weanling diarrhea (colibacillosis). However, rotavirus--a virus that destroys enterocytes--has been shown recently to be causally associated with weanling diarrhea of pigs. The role of both rotavirus and hemolytic enteropathogenic E. coli in weanling diarrhea was assessed in this study. Pigs from a closed her...