normal 0 false false false en-us x-none ar-sa background: elective knee surgery for repairing anterior cruciate ligament is usually associated with moderate to severe postoperative pain, and, therefore, selecting appropriate analgesia can considerably facilitate pain control and patient’s discharge.this study was designed to compare the analgesic effectiveness of administration of ropivacaine o...

PURPOSE Ropivacaine is a new long-acting aminoamide local anaesthetic, structurally related to bupivacaine. The clinical efficacy of 125 mg, 187.5 mg and 250 mg ropivacaine have been reported and compared with 125 mg bupivacaine for epidural analgesia during hysterectomy. In the pharmacokinetic part of this study the objectives were to 1) determine the dose proportionality in the pharmacokineti...

anesthetic agent as well as lidocaine, bupivacaine and mepivacaine (Fig. 1). Unlike bupivacaine and mepivacaine, which are racemic mixtures of the enantiomers containing equal proportion of the (S) and (R) forms, ropivacaine is exclusively the (S)-enantiomer. Since the (R)-enantiomer in the racemic aminoamide has known to be toxic, ropivacaine potentially provides lower toxicity on heart and ce...

Background: Ropivacaine for intravenous regional anesthesia (IVRA) provides prolonged analgesia over lidocaine and have a lower toxicity compared with bupivacaine. To reduce the amount of local anesthetic and to improve the quality of the block additives like opioids are used. Aim: The present study was designed to assess the anesthetic efficacy and post-tourniquet analgesia of adding fentanyl ...

BACKGROUND Pain after shoulder surgery is often treated with interscalene nerve blocks. Single-injection blocks are effective, but time-limited. Adjuncts such as dexamethasone may help. We thus tested the hypothesis that adding dexamethasone significantly prolongs the duration of ropivacaine and bupivacaine analgesia and that the magnitude of the effect differs among the two local anaesthetics....

Marhofer and colleagues Malenfant Rancourt and colleagues Site Ulnar nerve (volunteers) Posterior tibial nerve (volunteers) Medication 3 ml ropivacaine 0.75% 10 ml ropivacaine 0.5% Dose of adjuvant 20 mg dexmedetomidine 1 mg kg dexmedetomidine ( 50–70 mg) Results Sensory block 350(SD 54) min ropivacaine only(5.8 h) vs 555 (118) min ropivacaine+ dexmedetomidine (9.25 h) 972 (SD 120) min ropivaca...

BACKGROUND The purpose of this study was to evaluate the use of different concentrations of ropivacaine in ultrasound-guided regional anesthesia with regard to postoperative analgesic and patient's satisfaction in elderly patients undergoing inguinal hernioplasty in the People's Republic of China. METHODS A total of 60 patients (>75 years of age) who scheduled inguinal hernioplasty at the She...

OBJECTIVE To determine if preemptive analgesia with ropivacaine hydrochloride with or without clonidine hydrochloride decreases pain and hastens recovery after tonsillectomy. DESIGN Prospective, randomized, triple-blinded trial. SETTING University referral center; pediatric ambulatory practice. PARTICIPANTS Sixty-four children, aged 3 to 15 years, undergoing tonsillectomy. INTERVENTIONS...

BACKGROUND Magnesium, ropivacaine, gentamicin, and rocuronium block neuromuscular (NM) transmission by different mechanisms. Therefore, concurrent administration of these agents may induce prolonged muscle paralysis via synergistic interaction. This study investigated the efficacy and safety of NM block caused by the administration of high concentrations of magnesium in combination with ropivac...

BACKGROUND Early studies suggested that ropivacaine had clinical advantages over bupivacaine with respect to cardiotoxicity and motor block, and that it was suitable for epidural caesarean section. This study was set up to compare epidural 0.75% ropivacaine with a popular bupivacaine/fentanyl mixture for elective caesarean section. METHODS Eighty women having elective caesarean section under ...