OBJECTIVE Approximately 10% to 15% of Kawasaki disease (KD) is refractory to treatment with initial intravenous immunoglobulin (IVIG). However, there is no consensus on pharmacologic treatment of refractory KD (rKD). Demographic characteristics of patients with rKD and regional variability in their treatment in the United States have not been reported on a large scale. The goal of this study wa...

Immunoglobulin G4-related disease is a recently recognized systemic disease that can affect any organ or tissue in the body, including the kidneys. IgG4-related kidney disease (IgG4-RKD) is an important part of immunoglobulin G4-related disease. The most common renal manifestation of IgG4-RKD is tubulointerstitial nephritis and glomerular lesions. There, however, is few case of IgG4-RKD mimicki...

INTRODUCTION IgG4-related disease (IgG4-RD) is a fibroinflammatory disorder that may involve almost each organ or system. IgG4-related kidney disease (IgG4-RKD) refers to renal lesions associated with IgG4-RD. The most frequent morphological type of renal lesions is IgG4-related tubulointerstitial nephritis (IgG4-TIN) which is associated with increased IgG4-positive plasma cell infiltration and...

We treated a 61-year-old man with immunoglobulin (Ig)G4-related kidney disease (IgG4-RKD). He had a history of allergic diseases and an allergic reaction and had received a diagnosis of autoimmune pancreatitis (AIP). He had also received a diagnosis of renal cell carcinoma (RCC) and had undergone segmental resection of the left kidney at 59 years of age. His serum amylase level and number of pe...

Most of the man-made objects are having some straight lines with colors. A very high-speed object recognition method using color line patterns is carried out a novel self-learning device (RKD - Rasiq Krishnakumar Device). Instead that Artificial Neural Networks (ANN), RKD based networks used for different steps in this pattern classification. The and straight-line features extracted by segmenta...

Related-Key Attacks (RKAs) allow an adversary to observe the outcomes of a cryptographic primitive under not only its original secret key e.g., s, but also a sequence of modified keys φ(s), where φ is specified by the adversary from a class Φ of so-called Related-Key Derivation (RKD) functions. This paper extends the notion of non-malleable Key Derivation Functions (nm-KDFs), introduced by Faus...

IgG4-related kidney disease (IgG4-RKD) is a comprehensive term for renal lesions associated with IgG4-related disease, which is a recently recognized clinical entity characterized by a dense lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells with fibrosis affecting several organs. Tubulointerstitial nephritis with increased IgG4-positive plasma cells and fibrosis is the most domina...

We prove the related-key security of the Iterated Even-Mansour cipher under broad classes of related key derivation (RKD) functions. Our result extends the classes of RKD functions considered by Farshim and Procter (FSE, 15). Moreover, we present a far simpler proof which uses techniques similar to those used by Cogliati and Seurin (EUROCRYPT, 15) in their proof that the four-round Even-Mansour...

IgG4-related disease (IgG4-RD) is a nosological entity defined as a chronic immune-mediated fibro-inflammatory condition characterized by a tendency to form tumefactive, tissue-destructive lesions or by organ failure. Urologic involvement in IgG4-RD has been described in some short series of patients and in isolated case reports, most often involving the kidneys in so-called IgG4-related kidney...

Malignant brain cancer persists as a major disease of morbidity and mortality. The failure to recognize brain cancer as a disease of energy metabolism has contributed in large part to the failure in management. As long as brain tumor cells have access to glucose and glutamine, the disease will progress. The current standard of care provides brain tumors with access to glucose and glutamine. The...