a 13 year- old girl had rickets clinically evident sicne she was 10 years of age. she received multiple doses of vitamin d3 without improvement.this patient manifested an unusal form of hypophosphatemic rickets with hypercalciuria. it is recommended that urinary calcium excretion be assessed in all patients with hypophosphatemic rickets before the initiation of any therapy

Introduction: Vitamin D deficiency and rickets continue to be health problems in developing countries and most of the infants with congenital rickets may present with hypocalcemic seizure.   Case Report: In this article, the report on four infants who presented with hypocalcemic seizures but subsequently were found to have congenital rickets is presented. All of them had hypocalcaemia and low l...

this study was aimed to determine prevalence of vitamin d deficiency and rickets in children with cholestatic liver diseases. forty eight children with established cholestatic liver disease who referred to gastrointestinal clinic of children medical center (tehran, iran) between april 2010 and march 2011 were enrolled in a cross-sectional study. laboratory analysis including calcium, phosphate,...

introduction: vitamin d deficiency and rickets continue to be health problems in developing countries and most of the infants with congenital rickets may present with hypocalcemic seizure.   case report: in this article, the report on four infants who presented with hypocalcemic seizures but subsequently were found to have congenital rickets is presented. all of them had hypocalcaemia and low l...

Rickets is a metabolic bone disease that develops as a result of inadequate mineralization of growing bone due to disruption of calcium, phosphorus and/or vitamin D metabolism. Nutritional rickets remains a significant child health problem in developing countries. In addition, several rare genetic causes of rickets have also been described, which can be divided into two groups. The first group ...

Introduction: Vitamin D deficiency and rickets continue to be health problems in developing countries and most of the infants with congenital rickets may present with hypocalcemic seizure.   Case Report In this article, the report on four infants who presented with hypocalcemic seizures but subsequently were found to have congenital rickets is presented. All of them had hypocalcaemia and low le...

Rickets develops when growing bones fail to mineralize. In most cases, the diagnosis is established with a thorough history and physical examination and confirmed by laboratory evaluation. Nutritional rickets can be caused by inadequate intake of nutrients (vitamin D in particular); however, it is not uncommon in dark-skinned children who have limited sun exposure and in infants who are breastf...

Rickets is typically due to nutritional cause, namely vitamin D and calcium deficiency worldwide. When there suboptimal response conventional supplementation, alternative causes have be sought. We report a rare case of D-dependent rickets (VDDR) who presented with rachitic features but normal total 25-hydroxyvitamin 25(OH)D level. Conventional inactive supplementation was ineffective high dose ...